This guide is a work in progress for a Mid Lane and late game support Karma. As such, it will take a long time to perfect so if anyone is actually reading this, please bear with me. Any feedback is appreciated.

Playing Karma mid lane:

Karma is best utilized through her Heavenly Wave and Soul Shield harass. The best strategy I have used so far is to stay around the ranged creep and wait for the opportunity to either attack the enemy creep, or Heavenly Wave the enemy creep. This works in low levels mostly due to the 3 mana potions. When enemy champions come in to attack or harass, it is best to use Karma's Mantra and then Soul Shield the friendly creep closest to the incoming enemy champion. Unfortunately, this takes up a lot of mana and so it shouldn't be done often (hopefully one would be up against a passive enemy champion). Also, depending on the enemy, a simple Heavenly Wave harass works just fine. For example, when fighting Ahri mid lane, I find it easier to constantly strafe walk and Heavenly Wave harass, rather than exert the effort and mana to Mantra Soul Shield.

Pros

* Karma is self sufficient in most 1v1 scenarios in the middle lane

* Pushing lanes

Cons

* Karma has no escapes

* Draven, Cassiopieia