Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
All's you gotta do is harass and not die and pay attention to where you leave your ballz.
Also, remember when you use command attack to not run away because if you run away and use command attack at max range it will reset back with Orianna.
Masteries / Runes / Items
I get all the basic masteries for a caster and standard runes. The build I have for items is a little odd because of the Guinsoo's (I know). The item works well on her, it helps you push towers and dish out extra damage with your passive, plus it increases your ability power.