Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
HI! this is how i often play Pantheon i both ranked and normal games. I hope you will like it and pleas tell me if there is something you don't like so i maybe can change it :)
As a starting item i usually take meki pendant a healt and a mana potion. But some times i skip meki and go right on damage whit a Long Sword and a healt potion.
If i have got a good start i go back to shop a long sword and maybe a healt potion (depends if enemys are agressive and how much damage they deal on you). I try to complete The Brutalizer as quick i can because it gives damage, CDR and armor pen which is good for Pantheon whit is spear shot and heatseeker strike.
In mid/late game i should have completed at least B.F sword and Vampic septer and starting to collect to the bloodthirster if i don't allready have it.
After the Bloodthirster i start whit Infinity Edge by getting B.f sword first and then Pickaxe.
Then if you face a team whit alot of magic damage i upgrade my Meki pendant into Charice of harmony. To get some magic resistance.
Then the final item another Infinity Edge and as befor start whit B.F sword and then Pickaxe.
then you sould have around 400 damage and be pretty dangerous to you opponents on the fields of justice :P
i take 21/9/0 but sometimes 21/0/9 to get increased mana. Healt and mana regen. http://www.fieldsofjustice.com/m/#/uZawwHalZuPqZyaZwu (like this) Not much more to say about masteries.