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totaly disagree with the hybrid runes! Just take magic penetration :). As far as the build is concerned I like Kassadin with mana (more assasinate opportuinities) and q is better for early game. Keep it up though,it is generally good (I just disagree with your choices)
Hybrid Pen Marks are good on Kass. Not only does he AA (W), but it also helps him last-hit.
Reason i take hybrid penetration runes is for auto attacking early :P. u can take magic pen if u like. its just what i prefer. I actually have never tried the mana kassadin.... w works for me. Try it out in a custom game trust me (or not).