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I gave you a +1 for the effort.
You could learn some coding in Jhoihoi's how to make a guide :)
I don't have the link now, but you can find it by writing karthus guide in search :P
Just few things I'd like to point out, other than that your guide seems good :)
*You should get those boots earlier, I recommend Ionian boots instead of mercury treads
*The Brutalizer and youmuu's ghostblade really early, sunfire cape is quite hard to pull off as first item, because it's snowball champion
*Not so sure about Wit's End, the attack speed isn't really needed. You get that from possible youmuu's ghost blade.
*Desolation marks ? I guess they're fine also, but flat attack damage for snowball champion is better
*Slice and dce at lvl 4, not 3?
Oh btw, instead of putting pictures of garen for example, use this [ icon = garen size = 50 ] (Without spaces, except on the garen and size) it will give you the image and link to it.
Keep on working the guide, because it has potential :)
I won't upvote or downvote, but I can check the guide again later on, if u wish :P