This is the best Vlad guide your gonna find.
Nobody is going to stop truck Vlad from wrecking their entire team with 3 spell casts, while hardly taking any damage.

Pros:
Very tanky for apc
Aoe is great in team fights
Strong farming
Very easy to stay in lane

Cons:
Weak til early-mid game
Low cc
-Health on spell casts

This is the easiest part of your whole game. Just sit back and let them push and farm with your q. Once you get your e you can choose to push and get stacks with it, while intermixing q casts to make sure your health stays high (try not to fall below 80% simply from spell casts). I like to sit in the bush away from creep waves and just keep casting your e not against the creep waves, then show yourself when you need to last hit.
If you get a Shen or a Garen or Darius etc. you are going to want to see if they will push, then just use your q and e to shred them down about half way staying concious of ganks, then pop ult and w and that should finish them off.
If your dealing with some range, Jayce or Nid or another Vlad etc. your going to want to poke and poke with your q e combo and then ult in and q e combo until they are low enough for your to escape and then pop w so they cant land anymore dmg and get outta there.