Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Pantheon Jungle is a complete Boss. If you lead enemy champions into bush and leap onto them with a stun (W) you'll have an extreme advantage over them. A great combo with Pantheon is W,Q,(Basic Attack),E,(Basic Attack),(Repeat/Spam). Collect both Blue/Red buff for ultimate an ultimate combo, especially with the 10% cooldown reduction with Blue, you should come out on the winning side of a 1v1 fight. Before going in on a fight make sure you're shield is avaliable or 1 to 2 hits away, it can change the tide of a battle dramatically.
Spear Shot (Q)
Pantheons Spear Shot (Q) is the first skill you want to unlock and max. This skill is great for securing kills and because he is a melee champion, it gives him an advantage for range attacks if you're ganking other lanes. This skill is great early game for poking enemy champions under their tower. Late game is also great collect some kills and assist team mates.
Aegis of Zeonia (W)
Pantheons Aegis of Zeonia (W) is the second skill you need to unlock and third to max. This ability allows you to leap onto enemies, stunning them for one second. If an enemy champion is escaping this skill is great for capturing them and dealing damage to secure an easy kill. Ganking lane is also great with this skill because of the stun, hiding in a bush then leaping onto an unsuspecting target will lead your team to victory.
HeartSeeker Strike (E)
Pantheons Heartseeker Strike (E) is the third skill to unlock and second to max. This ability allows you to channel 3 swift strikes over 0.75 seconds, in a cone shape. This ability is great for clearing minions in large hoards or grabbing last hit for extra CS. When using against enemy champions, it is great for dealing damage to them when they're just out of range and can get you multiple kills if their health is low enough.
Grand Skyfall (R)
Pantheons Grand Skyfall (R) is the unlocked at level 6 and last to max. This ultimate is best used in team fights, if your team is in an intense battle, land behind the enemy and cut off their escape route or land right upon your enemies, dealing a crushing blow. How does it work? After selecting an area to land in the given limits, Pantheon gathers his strength for 2 seconds before leaping into the air, 1.5 seconds later he will crash down at the target area. This ultimate takes time though, so you're going to have to predict what your enemy is going to do and where will they go. The outline of the landing zone is visible to enemy champions, so they have time to clear, but if you land in a bush they'll be unable to see it. (Unless they're in the bush.)