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Nevertheless, it should always be before Madred's/Bloodthirster imo.
Very convincing.
Anyway, Gary, I think it might be better to leave it at a Warden's Mail for a while, then get banshee's, then some kind of damage item and then complete Randuins. I'm not sure, but I think you'll do too few damage with her if you don't. I don't play Vayne myself, but I've often used a build like this on Irelia.
yep trinity force is a must it syncs so well with vayne, upgrading it is just a preference i guess and depends whether you need more damage or more defensive items during the game.
Nevertheless, it should always be before Madred's/Bloodthirster imo.
Combine that with your Q and you hit roughly 3x as much as you should normally when you tumble.
It has insane synergy with her Tumble like it does with Ezreal's Mystic Shot, if not better.