Hi there! :)

Good that you have taken the time to write this guide - I can see a lot of potential. I would recommend you to click the link in my signature saying "jhoijhoi's guide to making a guide". It will surely improve the appearance of your guide, since currently it is a wall of text, and eyes like pictures for some reason. Currently, you are using CAPITAL LETTERS and it seems as if you are screaming.

Some comments on the contents of your guide:

- You buy a Negatron Cloak, but you do not finish it into anything. Also you buy only 5 items, you should add 6 items that you prefer. Also I think Frozen Mallet is not such a good item on Vayne, since you have your passive.
- You take a point in Utility Mastery, but later on you say you should let teammates have the buffs. It is contradicting, as the Utility Mastery will be useless. Also, Good Hands > Perseverence and Awareness > Expanded Mind. You will be running around a lot, ganking, so you will need the extra xp.
- 9-0-21 on Vayne... I'm not so sure about it. However, it could very well work. Maybe you can write a bit more in your "Masteries" section, why do you take 9-0-21 and not for instance 15-0-15.

Well, it seems like I'm really negative, but actually I think this guide has a lot of potential, it just needs some fine-tuning. Good luck in doing so, please feel free to PM me once you think you have improved it well enough.