Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
This is my build while I am learning to use twitch.
Works on his high attack speed, and his cloak to allow him to get to places.
Early game hold side lane. once past lvl 3, cloak->hit weakest->poison->expurge when they are out of range or turret gets to close.
Mid game, solo ganking, using boots and teleport to support the lanes and push turrets when not attack. Be Everywhere.
Late game, pushing lanes and killing towers with super attack speed.
End Game, Spraying and Praying all over there nexus.
With this build at one point, normally in mid game I find I need to get a gaints belt to up my hp otherwise I am so weak and low on hp.