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Deathfire Touch is great for poke but will only apply with Contaminate (E). This means that if overused, you will run out of mana very quickly. But combined with Twitch's passive, the damage over time is hilarious.
Grasp of the Undying will be reduced to stealing 1.5% of your max HP due to Twitch's range, but is great for sustain in drawn out fights against tanker opponents.
Fervor of Battle is a decent choice against fighter class opponents that you can kite, then chase down once they've realized their mistake.