Vayne is a amazing ad carry she is very mobile with some good cc

I like to run armor pen marks and quints because you don't need a last wispier or black cleaver i also run armor to be able to take the damage other ad carries damage the attack speed is just to land silver bolts faster

I run the Doran's blade first for that extra damage then i build strait into Wriggles for the life steal armor and the ward always helps also if you run Wriggles first you should be able to beat any ad carry that goes a quick bf sword i like Berserker's Greaves for that extra attack speed then build into a IE so you can out damage almost anyone then a Blood Thirster for the sustain and damage plus with Blood Thirster and Wrigles you should be able to take anyone 1v1 next i go Phantom Dancer for the crit and attack speed then i sell my Dorans and Wriggles and pick up two more Phantom Dancers if the game has lasted this long you should not have any problem winning

i run flash for the mobility and escape and heal for that lane dominance and to keep alive

I max my first to lower its cooldown and get the damage going the e because the cooldown is quite large and haveing it will save you alot i max w last because i don't feel like you need the extra damage from it you should be fine with wrigles and q

make sure to farm a lot the build is expensive so you will need that money

try to get your support to pick someone aggressive like bliz he is my top choice for supports because if he is sitting in that bush lanes a pull then knock up your e will stun them and its almost always a kill in team fights try to stay out for a bit come in after the ap carry has used his spells you don't want to get nuked

When in your ult if you are going 2v1 or 3v1 try tumbling around keep moveing try landing your stun on their most cc