This is my first build so please leave comments. That would be greatly appreciated :D Anyways. This is a Vayne build as you can see. I hope that you try it out and that it leads you to many victories and kills.

I picked these runes because Vayne is a DPS. Plus she does a lot of damage with her ult and her tumble. The more armor penetration, the better. Also, at rank 5, Vayne's Tumble's cooldown is ridiculously low. But with these seals and glyphs, the cooldown will be even more. (Honestly, the Seals can be anything. It can be attack or cooldown or attack speed. Whatever you want.) And lastly, The Quintessences just give amazing armor penetration.

I go with this Item build and it is really helpful. With this item build, you will be fast, well faster than most other champions, and have a lot of attack damage. Now, as you can see, I didnt put the 6th item. The 6th item is up to you. If you want more attack speed and movement, get another Phantom Dancer! If you want more attack and lifesteal, get a Bloodthirster. It's all up to you. But the rest of the items are a MUST.

Now, for the skill sequence, I couldn't tell when I could get which skill at which level. So this will clear it up. You want to max out Tumble first. Tumble will help you get a quick get away. Plus, with your ult, you will be stealthed. Or, if you want to get a sneak attack on your enemy, you can tumble. Tumble at Rank 5 has a really low cooldown so you can spam it a lot. Then, you want to max out Condemn. That thing really helps out and the extra damage if you can hit the other champion in the wall can do a lot. Condemn can also save you and knock the enemy back. Last, Max out Silver Bolts. When your attack speed is higher late game, you will be doing so much extra bonus damage with that skill. Whenever you get a chance, put a skill point into Final hour. Duh :P

The best summoner spells I think for Vayne are Ghost and Flash. You can flash towards the champion tumble and Condemn then shoot. Also, if you need to run away or get closer, Ghost is really helpful. Vayne is really squishy so both of these spells will help you make a quick getaway. You can use exhaust too but later on, you will be doing so much damage, plus with the stun and tumble, and ghost or flash, they will be dead before you need to use it.

Yea so... This is a Vayne build. She's really strong if you can play her right. Just getting first blood or one kill will make a difference in the game. I really hope you like this Build. Thanks for reading guys!