Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Alright guys so for the mastery, I like to go the typical 9/0/21 build.You get magic penetration in the offensive tree.As for the Utility I went to get 4/4 on the experience since Veigar really needs to level to make his skills stronger.
Now for the skills you want to max Q asap.Then you get your E to level 2 and then you max W.The reason you get E to level 2 is because the stun is just long enough so that when you cast your W and it can land on the enemy before they can move.
For red's I get magic penetration.Magic penetration will help you desolate your enemies easier.For yellow's I get mana regen.I get mana regen because Veigar will be spamming his Q a lot in the beginning of the game and you want to make your Q as strong as possible.For blue's I get cool down reduction because it really helps you cast your spells more often therefore doing more damage.For quintessence I get health.The health will allow you to stay alive longer.
For summoner spells I get ghost and flash because those two summoner spells will allow you to initiate and escape from your enemy.
For these levels your main duty is to farm.You want to last hit the minions with your Q as much as possible.
You still want to farm until you max out your W since it is one of your best skills.Keep last hitting minions and farm to 14 asap.
By now you should have your death fires grasp which is the main item to Veigar.You will be desolating enemies really quickly.
Your main combo for Veigar is
With this combo you will be able to kill EVERY squishy champion.They will all fear you.