Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
I prefer playing vlad this way because it can offer a lot of survivability with dmg. Usually at end game u are sitting around 4000 hp. Spirit visage allows you to heal more with transfusion and give u increased cd reduction so u can sanguine pool more often and get away or prevent escapes and then with mejais and your ulti u should be able to get stacks. rylis is just a great choice with vlad because u get both hp and ap. And just remember that to keep casting transfusion in fights it should be at a 2 sec cooldown.