Hello, this is my first guide here at Mobafire.com so don't think its a 2200 ELO master guide.
This build is used by me now and not really Guardsman bob sinc ive kinda changed it to my taste.

Ok so lets go through the runes that we will be using.

We want magic pen red since Warwicks Q and R is magic damage based, having this will making harrasment so easy early in lane.

For yellow we are using Flat armor since we wanna be able to tank a little more since we start of with dorans or boots 3x pots.

For blues we are using MR per level, taking flat MR is also fine but i prefer the MR per level since i do better late game than early game.

For quints we are using movement speed, u can skip these if ur using 9/0/21 masteries and use magic pen quints instead. Warwick is kinda slow early game, having these will make us move a little faster so we can mabye avoid that early gank.

For Masteries i use my standard ap tank 9/21/0 seeing as how we want the hp from defence and all that good shizzle but we also want the damage from the magic pen in the

Now for the items.

We start of with a dorans ring or the standard boots and 3x pots, you can also start with cloth íf you are meeting that pesky GP or Darius or even Irelia.

When you got about 800-1k gold you can B, i dont recomend B'ing before that! When u got the 1k gold go back buy ur mana crystal to build up that Glacial and boots for the movement speed, If you started boots however we can get chain and crystal.

Later on i normaly buy my Sorc boots before Glacial since WW Q is magic damage ( like i said before ) making us Q for ALOT of damage ( aka free health pots )

You now got the basic items, you can now chose to buy Wit's End for you next item then build on for the godly AEGIS OF POWWA, then get that frozen since u want that mana and armor, then for hp item we can get anything, frozern mallet, warmogs, or anything else, last we get that nice and kewl guardian angel.

So we got these skills

Passive: Eternal thirst. This is just amazing, you get life steal for free and this makes so you can lane even longer!

Q: Hungering strike. Warwicks main attack, this will cut the enemies health apart and give you a HUGE life steal back, its awesome range makes so u can dive the turret and flash away so easy. Use it to harras, kill, or just get health back
Also low in HP after a teamfight and their team is still going on you? goto the jungle and Q some creeps, TADAA u got ur HP back and are ready to fight again without using B!

W: Hunters call. This is good if you want to clear creeps or take buffs, its also Warwicks skill to eat towers down within seconds! I mostly use it for buffs, huge creep waves, tower eating, and for teamfights, It wont really do much in 1v1 early game since u got no attack damage :P

E: Blood scent. This skill is making Warwick a sick hunter, not only can he detect if someone is low but he can also run away from ganks, its also a cheap way to run away from teamfights when ur team lost and one of the enemies is below half health.

R: Infinate duress. R then Q = 9/10 of the enemies health gone...most of the time, i love Warwicks R, its the perfect ganking skill and also good for locking down the enemie carry.
Dont forget that this can also save your teamates from enemies that is hunting them, use it to save over getting a kill!

For summoner spells i like to use ignite with Warwick, i tried teleport once but it didnt work out to well. Ignite will make ur R+Q a almost 100% kill, with the 9/0/21 masteries you can spam this away all you want.

For the second summmoner spell i use the OP ****ing game killing....Flash, its just to OP to pass by if ur champ dont got a built in flash skill -_-

What i DONT recomend using:
Ghost, why? well u got ur E for freaking sake! and take ghost instead of ignite is just not worth it in my eyes.

Summoner spells you can use with lanewick:
CV can be used....yes i play SupportWick time to time and hes great, with his R he can save lives.
Teleport: depends if you need to B often and the enemies is still in lane, u dont want to be underleveld!

Thanks for taking your time to read my first guide, if you liked it please rate it, and if you didnt like it PLEASE tell me why, i will be updating this in the future. I will add more chapters the more views it gets, if ppl ask alot i will make a FAQ.