Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
I like play with Pikac... err, Nasus.
It's a very nice hero with very good abilities, furthermore Fury of the sands also incrases his size... :D
Since the beginning, starting with siphoning strike and try to last hit many creeps as you can. 9x Greater Glyphs of Clarity will help you with mana conserve. Remember wait around level 5 ( you can start since level 3, but usually wait for the rank 3 ) to use spirit fire as farming skill, and also remember to save mana for siphon strike has priority.
Healt potion will help you if enemies dont let you lasthit/lifesteal. just 70 golds, or at least 35 for one... better pay 35g instead recall back :)
I always try to come recall only when have cash for both mercury's threads and sheen.
Then depends what you need. You can jungle ( killing a golem means an easily farm )or go again lane.
Brutalizer is a must, for both armor penetration and cd reduction, but if you need more hp/resistance/armor, you can just end it and save the last step of the Youmuu's Sword to early game.
1)Remeber to last hit everytime you can ( also remember that you can activate Siphon strike during the attack animation )
2)Fury of the sands can also be used as potion, so if ignited/low on healt and near to get saved... have to considerate the chance to use a 120sec ( or less with cd reduction ) cd that could save you.
3)Youmuu's Sword can also be used as "escape boost"
4)Siphon Strike can also be used against turrets
5)Remember to fight over Spirit fire (all the times you can ), cause it lower enemy armor till 40 ( rank 5 )
6)After trinity force, Mercury's Threads and The Brutalizer, items depends by situation, allied and enemies... so chose carefully by yourselves :D
Thanks Everybody and sorry for not so good english :p