Hey there, it's ClockworkDemon and this is my first build. This is the way I play Nidalee, as a mid-game hybrid that ends up more AP, but you can keep her hybrid. This build is NOT intended at all to be a support, but utilizes her incredible damage from both of her Q's. You can play top with this build, as she is very self-sustainable, but you could leave it to that Jayce or Yorick ;) Rate, comment, and enjoy :)

Pros:

Insane damage from Q
Able to secure kills out the ***
Javelin Toss is incredibly fun
Self-sustainable with the help of life-steal/spell-vamp/and Primal Surge
Clearing minions is a breeze with Pounce/Swipe
Has a set of 6 abilities with the help of Aspect of the Cougar

Cons:

Have to be good with skill shots/predicting the path of the enemy if you want to be the best you can be
Team might think you're going support
Somewhat squishy

You just gotta have fun!

If you didn't notice, there are no runes. Reason being, I'm a broke player and I barely have any runes. Sorry for the inconvenience *shrugs*

With this build, we're going max damage. I like to do things that aren't normal, so we're rolling with the 24/6/0. This allows for a ton of damage with some defenses.

We're going to max her Q first, E second, with one point in W until end game. This reason we have the maximum amount of damage possible, and able to heal ourselves/teammates.

I'm quite aware this guide is very short, but this is just a work in progress. Just remember, always land your Q at long range, don't do anything stupid, and you should be fine ;)