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2. Supports actually have to travel the map even more because the addition of Sightstone implies more recalls with more situations you want to save gold in base and just opt for more Vision Wards. Karma can actually abuse the additional mobility by catching up followed by using her Q or W. I just simply don't see the reason for wasting 200 more gold into boots which are currently the worst ones in the game because their unique effect is rather weak. 200 gold is worth two Vision Wards.
Ofc, CDR boots are just an option in case of not risking to build more CDR than actually required but my point was rather to emphasize that even all of the other boot options offer more benefits.
3. Well, the idea behind building penetration and CDR based AP items (you missed out this part of my statement here) is the gold efficiency and overall lower gold investment. If taking a look at an item such as Zhonya's Hourglass one of the two build path components is way too expensive without providing any furthermore useful stats. The point of building CDR/ Mana Regen (AP) items is clear I believe. I would just swap ZH for a different item then!
4. Graves basically has more resistances than other AD Carries making him less vulnerable to Karma's early game damage, that's the actual encounter. Overall her damage seems lackluster after a short period of time in lane. If you compare Karma's damage to Vel'Koz' damage it's pretty low but ofc, she provides more utility to the game. If you compare Karma to Janna then the amount of utility provided by Janna is far better, her shield is stronger etc.. It's just that you have to consider these things to explain why she doesn't see that much games anymore compared to before at some stage.
Thanks for the credit. when seeing the guide in the first place I couldn't remember you :o