Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Ive been toying around with a alot of diffrent Nasus builds lately, and to my suprise this one was the one that worked out best. It gives you hp enough to tank but also great damage.
With other builds ive found Nasus to be too squishy in end-game for my taste, but this build fixes that and still gives you great damage because of siphon strike.
By the end of the game you should atleast be critting for about 1200 with siphon strike, even more with spirit fire on.
Get sheen as fast as possible as that makes it much easier to stack spihon strike from early levels. Try to get golem buff aswell once ur around level 10. If ur up against a lot casters then get mercury's treads instead of Berserkers Greaves, you might also want to switch Atma's Impaler for Guardian Angel or Force of Nature.