Nasus was the first champion I was relatively ok with. He is an easy champion to dominate with when you have played him a few times, and have gotten a grasp on his skills and when to use them. When farmed correctly he has one of the highest damage ouput capability I have seen with any champion.

Marks

For your Marks, I choose 9 Greater Marks of Malice. This increases your critical strike chance by 8.37%. This increases your chance to hit a critcal strike with your Q. This helps a lot late game, especially when you have a good damage output for your Q.

Seals

For your Seals I chose Greater Seals of Replenishment, because if you are a good Nasus player you will be using your Q as much as possible to farm and do extra damage. With these Seals his magic regeneration is increased it by 3.69 Mana per 5 secs.

Glyphs

One of the setbacks of Nasus is his attack speed, this is why I choose to use Greater Glyphs of Alacrity, this increases his attack speed by 0.64%, by using 9 of these Glyphs, his attack speed is an extra 5.76%.

Quintessences

For the 3 Quintessences I choose Greater Quintessences of Furor. These increase your critical damage output by 12.38%.

This skill sequence allows you to last hit minions with your Q as soon as they spawn, a tip I see many Nasus players upgrade there E first, this is a horrible thing to do because you will be constantly teleporting back to base to regenerate mana. For the second skill you are better of upgrading your W to harrass enemy champions when they run back to the turret. Only ever use your E in team fights to harrass multiple enemy champions and to help your team do some extra damage.

For those of you who dont know Nasus' ultimate ability regenerates health and increases attack power, (usefull for finishing of enemies, or to escape when you have low HP), on top of the healt and attack power boosts, it also surrounds yourself with a Sandstorm, this deals a bit of extra damage to all surrounding enemies, including minions

Pros~
-He is an excellent Minion farmer.
-Excellent last hitter on both Champions and Minions.
-When farmed correctly, he is probaly the best champion.
-I know everone has said this, but HE IS A FREAKING DOG.

Cons~
-Terrible when you are AFK for a bit of the game and when you haven't farmed well.
-Not the best champion early game.
-Is susceptible to ganks quite easily early game.

For farming I recommend last hitting as many minions as possible, it is best to always do this where possible, therefore you are able to harrass enemies even at a low level. From level 1-6, I usually do and extra 100-200 damage. From level 6-11, I usually hit roughly 200-250 damage with it from here. Once you hit level 18, you should be dealing well over 300 damage, sometimes even 400+ depending on how well you lane and who you were laning against.

I have looked at the top 3 guides for Nasus. After using these guides many times I have decided to make this guide for myself. I have taken inspiration from many guides including fairly odd ones i have found. Many of the items are from my picking and the runes and masteries are my choise as well. I have compared my guide to many of the other top ones, and in my opinion I believe it is just as good, if not better than these guides.

All in all this is my personal guide and has never failed me before. I have always been dealing huge amounts of damage with my Q and even at full level, Nasus' E is even powerful. This is my first guide so please leave me feedback on what I can improve on. :)