Not Updated For Current Season
I have seen many Ryze builds with just mana and almost no AP, my opinion is that it sucks. This builder has a middle ground that makes it unique :D It has both a lot of mana and a lot of AP. You're going to laugh at it :p
Skill Squuence is easy, first E -> W -> Q. after that the enemy is pretty low on HP, but ofc when u got ur utli R use that before everything :)
When u use W first u reduce ur enemys magic resistance followed by ur root who also does damage and finnish spamming Q.