Vayne Tips:

Remember Vayne is a Hypercarry. She scales extremely hard. If you loose lane you can still carry every single game. You wanna use your ult to hide from enemies and while you are invisible you want to go there where they would least expect you.

Another Good tip is that you can use your Q against the wall so it almost completely cancels the animation and the empowered autoattack will come faster.

Always keep track of your passive. it can be very useful and especially in early game you are always faster than your opponent.