Do not fall behind whatsoever or your life will be hard (this means keep warded, the jungler does want to kill you).

Keep lane even or with jungler/support help win lane and scale. CS what you can without being harassed too hard and accept that in some matchups, you won't get dominance. Ask your support to play passive before you finish Botrk + Boots.

Take scuttle if your jungler isn't. Vayne condemn drops its resists and allows for a speedy clear and more safety in lane, which is all you want.

Look for 1v1s against basically every champ other than Caitlyn and Draven as soon as you have Botrk, Boots, and Recurve.

You need your team to wall for you. You know that bad tutorial? "Stay behind your minions." Yeah, stay behind your walls. You don't do damage if you're dead.

DO NOT GET YASUO SYNDROME. You might be good, you might be fed, but no matter what, do not forget that you are a squishy adc that will die in a few hits.

Keep farming, Vayne doesn't stop scaling. Every single item is a powerspike, don't get lazy.

Look to take barons and dragons, you shred them with guinsoos.

Tumbling in place against a wall speeds up the animation and allows for more auto resets.

Condemn damage only goes through at the end of the animation and applies a silver bolt stack. It's a pretty dope execute if you get it.

Vayne actually can zone. If you land two stacks of silver bolts, just hover around attack range and the opponent will back up if they have half a brain because they're scared of the damage. You don't always have to get the damage off, if you can use it to just get you breathing space.

Run in one direction and ult Q back through the team. Sometimes you can juke them hard.