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Recommended Items
Spells:
Heal
Flash
Items
Ability Order
Night Hunter (PASSIVE)
Vayne Passive Ability
Threats & Synergies
Threats
Synergies
Extreme
Major
Even
Minor
Tiny
Show All
None
Low
Ok
Strong
Ideal
Extreme Threats
Ideal Synergies
Caitlyn
Playing very passive in this lane is usually your best bet, abusing your Level 6 dueling power.
Synergies
Ideal
Strong
Ok
Low
None
Recommended Build
IE: Super high damage on squishies.
Rapid Firecannon: Buy when against champions you want to stay away from (e.g Caitlyn + Azir, Tristana + Lux, Draven + Syndra + Nidalee).
Statikk Shiv: Buy if your team lacks waveclear.
Mercurial Scimitar: Lots of CC on the enemy team.
Bloodthirster: Really good lifesteal, nothing else to say.
Death's Dance: Buy if you are getting blown up by assassins over and over, otherwise Bloodthirster is usually the better option.
Mortal Reminder: Personal favorite for damage against tanks that heal (e.g Maokai, Mundo, Zac, etc.).
Guardian Angel: Buy for the same reason you would buy Death's Dance.
Guinsoo's Rageblade: Stacking with BoRK passive and Silver Bolts makes for a fun way to play while ahead, it's not a very good item on Vayne though because you waste all of the AP.
Wit's End: Buy with Rageblade or to MR Shred for your fed APC.
Rapid Firecannon: Buy when against champions you want to stay away from (e.g Caitlyn + Azir, Tristana + Lux, Draven + Syndra + Nidalee).
Statikk Shiv: Buy if your team lacks waveclear.
Mercurial Scimitar: Lots of CC on the enemy team.
Bloodthirster: Really good lifesteal, nothing else to say.
Death's Dance: Buy if you are getting blown up by assassins over and over, otherwise Bloodthirster is usually the better option.
Mortal Reminder: Personal favorite for damage against tanks that heal (e.g Maokai, Mundo, Zac, etc.).
Guardian Angel: Buy for the same reason you would buy Death's Dance.
Guinsoo's Rageblade: Stacking with BoRK passive and Silver Bolts makes for a fun way to play while ahead, it's not a very good item on Vayne though because you waste all of the AP.
Wit's End: Buy with Rageblade or to MR Shred for your fed APC.
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