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Katarina is very squishy until she gets Abyssal. You can easily stun Katarina if she ults which cancels her ult and you will basically render her useless. She is also a melee champion so you can poke her (Only poke with Q, until you can for sure 1 shot once you get 6). Be careful of her E, because it puts her behind you so only stun her with Q or flash+ult.
Yasuo
Even though Yasuo is very strong because he blocks Annie's Q with his wind wall, he cannot block anything else. Annie's W and R can go straight through his wind wall and he cannot do anything about it. Just stun Yasuo with your ult and dominate his right after.
Akali
Akali is an easy win lane for Annie. Akali cannot do anything against Annie because of Annie's AOE abilities. When Akali is invis Annie can just W or R and Akali is forced to take the damage. Akali is also very squishy so Annie should be able to 1 shot her all game.
Azir
OK, good Azir players can wreck Annie. It is nearly impossible for Annie to beat Azir in laning phase, of course, if the Azir is good. He has high range and great mobility while Annie has neither of those things. Azir just pokes Annie down all game and RIP Annie. Why I don't put this guy at the top of the list though is because once Annie stuns Azir, Azir is dead. Annie can easily flash ult and wipe out Azir.
Xerath
OK, this guy has INSANE damage and range. Annie can't even get close to this guy without losing 3/4 of her health. Xerath just pokes down Annie all game using his passive and Annie cannot retaliate. If you can dodge the Xerath skill shots, then you could probably trade a kill for kill though.
LeBlanc
Personally, I don't find her very hard except on some occasions. If you are going to fight LeBlanc, ALWAYS stun her with your Q! It is very easy for LeBlanc to dodge Annie's abilities because of her 2 blinks and 2 dashes. Also if you cannot 1 shot LeBlanc, then she will get away. In a matchup like this I recommend roaming and always notice when she leaves to call mias.
Brand
Fire vs. Fire. Brand should naturally win the fight because he is tankier than Annie and he can do a lot more damage early game. He can poke you a lot more and he can 1 shot you if he lands his stun. He also can be more reliable to his team late game than Annie because of his massive AOE from his passive and ult.
Orianna
Poke after poke after poke after poke. All I can say about this matchup is, you cannot let her get ahead. If she is beating you up in lane then you need to retaliate and deal some damage to her. Be careful of her shield though as she can outplay you with it.
Lux
It's Lux, what do you expect. I would expect constant, annoying laughter and super cc pokes. Once she lands her snare you are dead :). She can be killed very easy though as you do one shot with this build.
Anivia
As long as you don't get hit by her stun you should be fine killing her. You do massive damage and once she is in egg form keep using abilities.
Aurelion Sol
His circling stars thing does a lot of damage and he will try to abuse it. Just Q him in return and lane should be all right.
Cassiopeia
Three words. Cassiopeia. Beats. Everyone.
Cho'Gath
He is a tanky champion you should worry about. It is hard to one shot this beast and he can easily shred you after the stun leaves. Just hope he is not building super tanky or you will have a rough time. Also keep poking him down with you Q, as likely he will fear you and you will be able to one shot him after he gets low.
Diana
Just stun her with your Q and you will deal a lot of damage. Get void staff kind of early if she gets MR.
Ekko
Fairly simple fight, just make sure you kill him before he gets his shield or when the W is down.
Fizz
He can get very tedious from dodging your Q with his W so I recommend trying to bait out his W or pop stun him with your W. Your W does instant damage so he most likely will not get enough time to E unless he predicts it.
Heimerdinger
Yes you can easily one shot Heimer. I am rating him this high because of the turrets. They stay after he dies and if he has his ult turret up you can die to. Most of the game just try to out farm him and avoid the turret ability things.
Karthus
Easy kill but be very, very careful of his passive. He will also try to poke you early game so stick with the minions as his Q will deal less damage.
Kassadin
This guy is really strong against you because of his magic shield. He basically can ignore a lot of your abilities and nuke you down too. Try to abuse him when he uses a lot of his mana.
Malzahar
Auto attack him to get his new passive down. 100% take barrier and not smite. Once his ult is done you can try to nuke him and be sure to use barrier. Very difficult matchup.
Syndra
Very difficult to face as she can also 1 shot you. Try to flash out of the way of her stun and nuke her down. Another method of beating her is to get your stun off before she does. Also be careful of her Q poke as it will burst you down fairly quick. If you get low back off because she can easily kill you with her ult.
Talon
Squishy. Very, very squishy. Simple to kill , just be careful of his E as it does place him behind you so try to stun with Q.
Twisted Fate
You out damage him and he most likely won't be able to 1 shot you so once you get out of his stun just nuke him before he kills you.
Veigar
If he tries to stun you sit in the middle of the circle and burst him down before he does. Try to end the game very early as this guy will 1 shot anyone late game with his infinite AP.
Vel'Koz
He has a lot of range and can poke you down, but he is very squishy; abuse that. If you manage to dodge his E then try to get some damage on him unless he is fed.
Viktor
Pretty easy fight, his doesn't do much unless he stuns you. His stun takes a couple seconds to pull you in so kill him before he stuns you.
Instant stun > Delayed stun
Zed
Try to stun him after he has ulted. Can be very difficult to beat him if he is ahead of you.
Ziggs
Annie is really weak against poke champions so if you can stay away from your minions and try to stay ahead of him. Once you get Needlessly Large Rod you should be able to 1 shot him.
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