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You can blink over her charm with your E. If you can do that than you win the matchup, otherwise build tenacity or bring cleanse.
Akali
Annoying due to her sustain. You'll have to match her sustain with runes and items if you want to win the lane. Mistakes will be heavily punished.
Anivia
While she does not pose much of a threat, neither do you. You won't be able to punish her mistakes very hard but she will be able to punish yours.
Annie
Like most mages Annie is immobile, and due to that you're gonna have an easy time getting on top of her and landing your W.
Aurelion Sol
If you can get next to him, which you can do very easily, he will be very easy to deal with.
Azir
Really depends on the skill of each player more than anything.
Cassiopeia
She can ground you with your W, making it difficult to reposition and also prevents you from casting your ultimate. Keep this in mind when fighting her.
Corki
If he disengages you can re-engage before he can do it again
Diana
She does a lot of damage but so do you. The matchup is skill dependant but Ekko has a higher skill ceiling so if you are very experienced you should always win.
Fizz
Skill dependant matchup. Better player wins.
Katarina
She does a lot of damage, has a lot of mobility and she can inflict grievous wounds on you. But you can follow her blink with your E, nullifying her disengage. Skill dependant matchup.
LeBlanc
Most Ekko mains will think Leblanc is a hard counter to Ekko, she is not. She is difficult, but the matchup is completely skill dependant due to the fact you can follow the second part of her W with your E. This nullifies her disengage. While the matchup still favours her, there is outplay potential.
Lissandra
You can follow her E with your E, nullifying her disengage. You may want some tenacity .
Lux
You can blink over her Q with your E. Lux is one of the best champions at punishing mistakes. If you don't bring tenacity, she will oneshot you if you let her land a Q. If she never lands a Q though she will never be able to do anything to you.
Malzahar
A simple matchup, if you want to win hard you have to build tenacity. If you do not mind scaling than the lane is fairly simple and he will never pose much of a threat to you until you have already hit your power spike. You'll want strong waveclear if you plan on having a passive lane.
Nocturne
You can W yourself when he casts his ult and you can buy stopwatch to prevent him from ever killing you.
Orianna
You will want some sustain for an easier time trading. Her ultimate is choreographed and is easily dodged by your ultimate or your E.
Qiyana
You will want sustain as she does a lot of damage, exhaust can also be useful. Rushing a seekers is a good way to prevent her from bursting you before you can make use of your sustain.
Ryze
He is outscales you and is difficult to kill early due to his point and click root.
Sylas
Skill dependant matchup. Better player wins.
Veigar
You can blink over his box.
Vel'Koz
Dodge his knockup and you win.
Xerath
You can blink over his E with your E. He is extremely immobile so if you can do it than he will be completely useless. Even if you get hit by a point blank E, it will actually stun you for a shorter amount of time so it can still be fine.
Yasuo
Windwall can mess up your combos and limit your outplay potential, his passive can also help him win trades if he has a minion wave to kite you with. This matchup is skill dependant slightly favouring Ekko as the Yasuo needs to play very well, not just as good as the Ekko.
Zed
Skill dependant matchup, most of his kit is choreographed so it favours Ekko.
Ziggs
Skill dependant matchup, if he uses his W properly he should be able to stop you from going all in on him. His disengage is on a longer CD than your engage so it favours Ekko.
Zoe
Skill dependant matchup, if you dodge her abilities you win. All of them are choreographed so it favours Ekko.
Amumu
He can root an entire team, preventing them from peeling your target.
Bard
He can set you up for a massive stun with your W.
Camille
She can help guarantee that you land your W on a specific target.
Jarvan IV
He can help guarantee that you land your W on a specific target.
Morgana
Her kit can be very good at setting up your W.
Rakan
His charm can help prevent the enemy team from peeling your target and his CC can help set up your W.
Sion
If you can land your W, sion can land his Q. It is a pretty devastating combo, but other than that not much synergy.
Veigar
His E can help guarantee you land your W.
Synergies
IdealStrongOkLowNone
Amumu
He can root an entire team, preventing them from peeling your target.
Bard
He can set you up for a massive stun with your W.
Camille
She can help guarantee that you land your W on a specific target.
Jarvan IV
He can help guarantee that you land your W on a specific target.
Morgana
Her kit can be very good at setting up your W.
Rakan
His charm can help prevent the enemy team from peeling your target and his CC can help set up your W.
Sion
If you can land your W, sion can land his Q. It is a pretty devastating combo, but other than that not much synergy.
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