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You get more AD with Greater Mark of Attack Damage and roughly the same amount Attackspeed with 3 Greater Quintessence of Attack Speed.

"Vayne has shred." -> She deals %max health damage.

You talk about mechanic but I checked your profile. It seems like you can't out-cs your opponent eventhough you think, you are gold IV.
Look at your games! Seriously you only get like 15 cs at 5 minutes and 50 at 20 minutes average. That's not good enough for someone playing ADC. You need at least 70 CS at minute 10. A general rule.
Also read this Guide to winning. Maybe you will realize why it's so bad to have just a few last hits at 20 minutes.

"But, Vayne has a 450 range" -> It's 550 range.
"her abilities scale with levelling" -> her abilities scale with levels

Revive doesn't even exist anymore.

Skill priority R>Q>W>E -> It means you always skill your ultimate whenever possible and max else like always.
Why not sometimes consider w over q?

YOU SHOULD LEVEL YOUR ULT AT LEVEL 6, 11 AND 16!
The bonus AD of Final Hour is way too good as well the chasing power it has. You can't just pass it up.

"Silver Bolts (W): Silver Bolts is a true (armor-pen) damage proc that hits for small flat damage and a percent of the enemy's max HP. This is used for potential damage stacking with Tumble, and for shredding tanks in fights. However, it's not strong enough to tank-shred with on it's own always."
-> I don't get this part. It will be always be good against health stacker. And true damage ignores the target's resistance so you don't need to write armor pen.

I wouldn't rush Avarice Blade because you don't get any benefits out of it. You may crit once but the crit isn't this strong because you have such a low amount AD. So you will only get one strong hit and that's it. Vampiric Scepter or Bilgewater Cutlass gives you far more sustain and really important TRADING POWER. When you get back to lane after your first back you will be level 6. At 6 Vayne has such a strong duelling power, stronger than most level 6 ADCs. If you can coordinate well with your support or jungler it should be an easy kill. And sustain is better to survive the poke of the enemy support. You can last hit way more which is the safest way to get much money!

Late game core is Last Whisper or even mid game hence I build it on every ADC as 3rd or 4th item because everyone gets naturally Armor per level and everyone builds armor. I would put Phantom Dancer in the core if you aren't even building Infinity Edge. The stats are great and boost your damage output more than Zephyr. Get rather Mercury's Treads or Banshee's Veil.

And I think Infinity Edge boost your damage output so much more. It should be core.

LATE GAME IS ABOUT OBJECTIVES. WINNING THE GAME MEANS DESTROYING THE NEXUS NOT KILLING THE SUPPORT.

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Please read the bbc code help and guide. It will help.
Just click on it.

Some changes have been made, but I have also some arguments in the new guide. I put BotRK down as a situational, just to satisfy the players (most of which play like real bronzes) that say BotRK is 100% necessary to Vayne. My argument for BT over it is that it gives a better flat boost, so you don't need to proc as much. Lucian isn't good early. Lucian isn't that great of an ADC IMO because his problems with having perhaps one of the highest champion skillcaps in the game kind of override his burst potential. Particularly with the extremely awkward ultimate. Yet again, that tiering is for lower ELOs. Higher ELOs? He's amazing in the hands of professionals. That know how to use him. Zephyr is now a situational. It's good to have in case the enemy has a LOT of CC. Also, it's great to have as an item that buffs it all. The Cooldown reduction isn't wasted. The better argument for my case is that you hardly USE it. It's unnecessary if you do it all correctly. I generally use it in ganks.

My repetitiveness was a little over the edge. Still have some in the new 5.9 adaptation, but it's not as bad as earlier. Plus, it's detailed on matchups.

Hey, sorry to say this, but you shoul really work this guide through again, since it's really not good at the moment. As well the runes, as the masteries are messy. (Vayne has a rough early, don't promote it by not giving her the Butcher, Feast and Unyielding Masteries) To the item build: You are not even mentioning BotRK, whicht is and has been pretty much core on Vayne. Instead you recommend to take Statikk, as well as PD? Also in a full build there should never be a Zephyr AND Boots. To point out the first thing I saw in the matchup list: [Lucian]: Laning shouldn't be hard against a champion that has damage issues early. Also he's not even that good in current meta, honestly." Both informations are not correct. This goes on through the entire matchup section. TriForce is not a good item on Vayne - I agree. But the thought process behing buying this "AP item", is the Sheen Proc. Ongoing: "Vayne, though, has no CC other than her super awkward E wall-pinning. She's supposed to just be a bulk damage dealer.". This spell isn't just there for no reasons. If you want to write a guide on Vayne you should really talk about the Utility it provides, since it's not only the wallpin, but also making a distance, getting last hits, that would have dropped otherwise. It's immensly good for fighting in the Jungle and dueling. And the last point that made me wonder is, how you wouldn't recommend levelling your Ult every possible time? It gives a HUGE AD boost, plus the duration is increased, which synergizes extremely well whith your tumble. Okay, I hope I could help you improve your guide. Thanks for making the effort nevertheless. Have a nice day.