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I know Perseverence and Expanded Mind SEEM like good picks, especially for Ryze, but they really aren't. In theory they would work nicely, but mathematically, they do almost nothing. Good Hands , Awareness and Utility Mastery are amazing by comparison.
Also, Strength of Spirit is AMAZING on Ryze. Since he stacks mana, it gives him incredibly high sustain. I recommend picking it up.