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Spells:
Ignite
Flash
Ability Order
Guerrilla Warfare (PASSIVE)
Teemo Passive Ability
x9 Greater Glyph of Ability Power: See above.
x9 Greater Seal of Ability Power: See above.
x9 Greater Mark of Magic Penetration: Use these runes to counter minor magic resistance early game.
Runes
Then buy Berserker's Greaves and an Amplifying Tome
Follow up with a Vampiric Scepter and finish building Malady.
Start building a Madred's Bloodrazor with a Recurve Bow and follow up with a Pickaxe.
Finish the Madred's Bloodrazor and start on a Frozen Mallet.
Buy a Phage then a Giant's Belt or if you can, finish the Frozen Mallet.
Build a Wit's End, Bilgewater Cutlass then finish that with a Hextech Gunblade.
Other viable choices instead of the Hextech Gunblade are an Ionic Spark or Black Cleaver.
Just build what you think you need.
I usually always use these spells when playing Teemo but there are other viable options
Ignite: The damage-over-time that Ignite yields is excellent when used in conjunction with Teemo's Toxic Shot. It can also be used to kill low-HP champions in the first few minutes when you don't have poison.
Flash: One of the best summoner spells, for any champion. Flash allows you to teleport over walls, closer to an enemy, or to teleport away from an enemy.
Exhaust: Exhaust can be used in conjunction with Move Quick to kill an enemy champion on low-HP.
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