Akshan, like many new champions in this game have a brand new mechanic that makes you scratch your head and question Riot Games, "Why?" His E, Heroic Swing, is a menace to you. Fast swing and does quite a bit of damage. His passive gives him a shield that allows him to mitigate your burst combo if he get his 3 hits onto you. As well as his boomerang that can poke you behind minions. Akshan is a new roster to the Thresh Mid's hardest matchups.
Yone
Yone is a tricky and painful lane opponent in general, but for Thresh it's his worst nightmare. Beating Yone is off the table and roaming is much proficient to get your team ahead to beat out Yone.
Yasuo
Likewise with Yone, Yasuo is impossible for Thresh to death with. With multiple ways to disengage from your damage, and his windwall killing your engage from Death Sentence.
Tryndamere
Past level 6 Tryndamere is a pain to deal with. Along with him being able to split-push the rest of the game away without having to interact with you from laning phase onwards. His R, Undying Rage, will make any and all combos against him null and void.
Malzahar
Malzahar is an interesting case, he's difficult because you can never interact with him. Malzahar keeps you pushed in and unable to roam. Along with that if Malzahar is to ever get jungle assistants it is a guaranteed kill against you. But his voidlings can give you souls so
try to make the best of it.
Sylas
Sylas is one of your worst matchups as Thresh mid, early game (Lvs1-5) is the only point you outtrade him, but otherwise he out-damages you, out-mobilities you, and can steal The Box and use it against you with it's 100% AP Ratio. If the Sylas is maxing Q, it makes this matchup even more difficult.
Zoe
Zoe is capable of poking you outside of your range and hooking her from her Portal Jump is pointless due to her just jumping back to it.
Fizz
Fizz is capable of dodging point blank combos and has insane all in potential while not having to worry about your combo since his playful/trickster is a relatively lower cooldown later on into the game.
Lucian
Lucian mid is a blight.
Anivia
Anivia poses a massive threat at any point in the laning phase. Anivia's abilities do a massive amount of damage, her displace on her wall can kill you more times than not. Along with her massive amount of her damage she outclears you level 6 and beyond, and can use her Glacial Storm (R) along with her wall to force a flash from you. Otherwise Death Sentence and Flay can cancel her ultimate.
Vex
Vex, a small champ, with big waveclear. Vex will be able to out waveclear you at any point of the game and will roam to get a lot of gold to just flat out beat you at any given point. Her fear is a turn off for any engage onto her, and on top of that she has her shield is pretty beefy when it comes to trading. Otherwise Riot Games still needs to nerf Vex down so expect her to be annoying to deal with for a while.
Orianna
Orianna is much like Zoe, she outranges you heavily and can shield herself. Along with Annie is immobile and can be won with jungle intervention.
Annie
Annie is difficult but capable of being dealt with. Her molten shield proves to be an issue while trying to trade with her. Tibbers stun combo can be a death sentence for laning phase. She is immobile so having a jungler help with this lane can be crucial to winning.
Viktor
Immobile mage with high damage over time. Jungler required for you to win this lane. Death Ray outranges you, and Chaos Storm is devastating for you since you are also immobile.
Syndra
High burst damage and can trade from a far. Another lane for jungler intervention.
Xerath
Outranges you heavily, but once close range he does not have much disengage to keep you away. Jungler isn't necessary but will always help.
Kassadin
Kassadin isn't a threat inherently before 6, but once he hits 6 he is a pain to deal with. With reduced damage from Magic Damage sources and a Magic Damage shield from his Null Sphere (Q), Kassadin proves to be a difficult lane opponent later. Trading with Kassadin early is mandatory before he outscales you.
Rumble
Rumble outdamages you at every point of the game, and can reduce your MR with his Electro Harpoon (E). His Scrap Shield allows him to win any trade early as well, but his overall poke with Flamespitter makes him hard to deal with in lane. Trade with him during points he does not have his Flamespitter up and the lane shouldn't be too difficult.
Vladimir
Vladimir isn't hard in any means, he's difficult because he can out-sustain you during the laning phase and scales harder than you into the late game. Consistent trading during the early game while baiting out his Sanguine Pool so he loses out on 20% of his current health makes the red reaper a little pale.
Cassiopeia
Cassieopeia damage checks Thresh at most points in the game due to her healing and doubled damage with Twin Fang on poisoned targets. As well as having considerable disengage with Petrifying Gaze.
Zed
Zed is an easier matchup early game for Thresh due to him having to farm with his shurikens or will suffer a high damage combo from Flay Electrocute. Levels 3 and beyond for Zed makes laning safer while being able to poke from a far with his Living Shadow.
Veigar
Veigar needs to be shutdown early game since he stacks harder than you do. His Event Horizon (E) can limit your movement pretty hard, and being low smells of danger with his Primordial Burst (R) essentially being an execute.
Talon
Talon early game is not much of a threat other than his level 2 powerspike from his passive. Talon's Noxian Diplomacy (Q) can be cancelled with Flay. His Shadow Assault (R) can be revealed if your Death Sentence connects onto him during his invisibility.
Qiyana
Qiyana early does not outtrade a Thresh max auto Flay if they are to start Terrashape (W), along with her Audacity (E) can be cancelled by Flay. Level 6 and beyond she can be difficult due to her full combo off of Supreme Display of Talent (R). Trading trading early game is needed. If not done she will consistently throw her Edge of Ixtal (Q) at you to attempt to look at kills.
LeBlanc
LeBlanc is a mindgame matchup, Distortion (W) can be cancelled with Flay. Death Sentence can be used to cancel her mid dash as well as being used for an all-out combo with The Box early game to deter her from staying in lane.
Ryze
Ryze can be difficult if you stand on top of the minion wave, and output of damage can outdo you early game. All ins level 6 and beyond are easy, walk up to him pull up The Box and you can flay him into the wall while auto attacking to whittle him down.
Ahri
Ahri early game can do a high amount of damage, but has decently high cooldowns. Once she uses her Charm (E) trading with her is easy. Level 6 her Spirit Rush (R) dodges hooks and can set her up for an all-in. Otherwise Spirit Rush can also be cancelled by Flay.
Vel'Koz
Vel'Koz can poke you out without having to walk up, but once he uses his cc he can be easy pickings for the usual combo. Level 6 is the best time to surprise him with The Box combo.
Ekko
Ekko's early game gets decimated by your basic trading pattern, only issue Ekko poses is late game. Otherwise his early game is free picking but be careful of his damage from normal combo of Phase Dive (E) into Timewinder (Q) and passive 3rd hit.
Azir
Azir is heavily dependent on his Soldiers, Death Sentence and Flay make it so he is unable to attack for a small duration. Death Sentence in particular can be used as a relocator. Level 6 and beyond can be a threat if he has intervention from another lane or the jungler. Otherwise early game he may pose a threat if you cannot get into his close range.
Katarina
Like Ekko she gets beat out early game, and can be threatening late game. Death Lotus (R) can be cancelled with Death Sentence and Flay. As well as can be very predictive with dagger drops.
Lissandra
Lissandra isn't capable of outdamaging Thresh early game but can outrange him. Her main source of damage is up close and personal where your danger zone is. Her Frozen Tomb (R) can setup for easy picks but has a considerable cast time so you can flash during the cast for distance.
Akali
Akali's Five Strike Strike (Q) has a slightly higher range than Thresh's auto attacks but her passive makes her want to jump into trade range for Thresh. Both Shuriken Flip (E) parts can cancelled along with her Perfect Execution (R) with Flay.
Twisted Fate
Twisted Fate has a very predictable playstyle, with not many ways to get you off of him other than his gold card. Level 6 you can all in with The Box into Flay ignite combo.
Aurelion Sol
No one plays this champ. Except for high elo one tricks.
Xin Zhao
With an amazing kit that synergizes extremely well with Thresh, he can setup for Thresh to guarantee kills. While Thresh can lantern him into combat. Xin Zhao can charge into the fight head first knock-up the enemy for a free Death Sentence that will guarantee kills any time a gank is set up.
Hecarim
Hecarim being a snowball jungler can use Thresh's setup on top of his high base damage to get himself some free kills. An average gank can use Onslaught of Shadows (R) for a fear into a guaranteed Death Sentence and then into The Box.
Kindred
Kindred, another snowball jungler having a dash, a slow, and execute damage can mean any cc setup for her will suffice.
Kha'Zix
Kha'Zix early game damage in the river fights can mean a lot when fighting for scuttle crabs, you will be helping him secure crabs during the laning phase and using lantern to pull him from one side of the mid lane to the other. Death Sentence can pull people into Isolation for increased damage onto them.
Vi
Vi can set up ganks extremely well with her Vault Breaker (Q) into Assault and Battery (R) for guaranteed Death Sentences that will allow Vi to beat on the enemy.
Volibear
High base damage, point and auto stun, lantern him in and he can do the rest.
Rek'Sai
Rek'Sai's base damage is high, along with a gap closer and a knockup she can easily find prey for the both of you. As well as her being a dive champion lantern can allow her to Void Rush (R) aggressively while having a way to get out.
Elise
Elise's setup guarantees hooks, but a mis-flay can make a cocoon miss more times than not. Otherwise her max health damage into execute damage makes ganking mid for her a queen's dream.
Lee Sin
Lee Sin can Safeguard (W) onto lanterns and can use Death Sentence/Flay for a Sonic Wave (Q) to hit no matter what. With his high base damage and early game sustain you can win early fights for scuttle with Lee almost any game that you play. Fabled legend tells of a lantern-sec where he jumps to lantern thrown behind the enemy into a Dragon's Rage (R) into The Box.
Poppy
Poppy being lanterned in and then being able to stop enemy dashes with her Steadfast Presence (W) while also being able to pin the enemy against a wall stunning them with Heroic Charge (E). With her Hammer Shock (Q) doing a considerable amount of damage early game.
Olaf
Olaf has an amazing time once he's on top of an enemy, flaying an enemy close and lanterning him close will allow him to have a hay-day with his early game damage.
Morgana
Albeit not picked much anymore, Morgana has terrific setup with Dark Binding (Q) that will make the enemy spend eternity wishing they didn't have to deal with this. As well as her Soul Shackles (R) are inescapable while the enemy is hooked.
Rengar
Rengar does immense amount damage when the enemy can't run away early. Lantern can pull Rengar into a bush so he is able to jump onto the enemy and Death Sentence guarantee's a full one shot combo from this ferocious feline.
Nocturne
Nocturne has his own engage with his Paranoia (R) and can fear enemies for a nightmarish combo of a Death Sentence into pure blender death.
Diana
Diana is capable of gap closing the enemy but does not have the damage early game to benefit off ganking Thresh, but once level 6 rolls around can use lantern engages for surprise moon ceremonies for the enemy.
Jarvan IV
J4 has some of the best setup in the game but does not have the damage to support it. Although he does not have amazing gank opportunity he does have amazing engage potential with his Cataclysm (R) without having to Flag n' Drag on his way over to the fight. Lantern for fights and he can make fights shaky for the enemy.
Fiddlesticks
Fiddlesticks early game isn't anything to write home about, but Terrify (Q) for a free fear can guarantee a Death Sentence onto the enemy while he drains them with a high burst of damage they cannot escape. Later on his Crowstorm (R) can be used in creative ways with Thresh. Crowstorm out of sight and then get dragged in with a lantern for the ultimate unexpected flank.
-Piece of Sheet can suck it.
Kayn
Kayn needs a longer lane to be able to make use of the crowd control Thresh has in his kit, but can use this as an opportunity to get orbs for his form pretty easily.
Nidalee
Nidalee can be a tricky cat to work with, especially since you can knock her out of her Javelin Toss (Q) with Flay and not even realize it. Albeit Death Sentence is capable of making cougar form do a lot of damage without a spear hitting.
Shaco
Shaco has his own way of getting in, but not really a way of getting out. Shaco Deceives (Q) in, Flay the enemy closer while he sets down a box and when they're feared Death Sentence allows the killer clown to get free backstabs onto the enemy.
Skarner
Skarner doesn't deal the necessary damage early game for Thresh's Crowd Control to really matter. Level 6 and beyond when Skarner can Impale (R) them towards an inevitable death towards The Box.
Viego
Viego is another champion that just doesn't deal enough damage to capitalize on Thresh's early game crowd control, but late game these two can be a menacing combo that will truly heartbreak the enemy.
Graves
Graves does not deal enough damage early game for ganks to matter. Later in the game, he can be a solid carry that you can capitalize on with lanterns to keep him safe.
Lillia
Lillia up until level 6 is incapable of ganking mid lane since she does not have the damage needed to even have a dream of killing the enemy.
Rammus
Rammus rolls on by not having enough damage to kill an enemy early game, but once you hit level 6 Rammus' taunt will allow a hook to land and make the enemy gasp in awe and only able to say "Ok"
Shyvana
Shyvana doesn't deal enough damage early game but level 6 and beyond her dragon form takes care of that entirely. Flay n Drag them through the fire for a nice crispy kill.
Ivern
No.
Why have an Ivern when you can have literally anything else, no damage, some setup but it's small.
Synergies
IdealStrongOkLowNone
Xin Zhao
With an amazing kit that synergizes extremely well with Thresh, he can setup for Thresh to guarantee kills. While Thresh can lantern him into combat. Xin Zhao can charge into the fight head first knock-up the enemy for a free Death Sentence that will guarantee kills any time a gank is set up.
Hecarim
Hecarim being a snowball jungler can use Thresh's setup on top of his high base damage to get himself some free kills. An average gank can use Onslaught of Shadows (R) for a fear into a guaranteed Death Sentence and then into The Box.
Kindred
Kindred, another snowball jungler having a dash, a slow, and execute damage can mean any cc setup for her will suffice.
Kha'Zix
Kha'Zix early game damage in the river fights can mean a lot when fighting for scuttle crabs, you will be helping him secure crabs during the laning phase and using lantern to pull him from one side of the mid lane to the other. Death Sentence can pull people into Isolation for increased damage onto them.
Vi
Vi can set up ganks extremely well with her Vault Breaker (Q) into Assault and Battery (R) for guaranteed Death Sentences that will allow Vi to beat on the enemy.
Volibear
High base damage, point and auto stun, lantern him in and he can do the rest.
Rek'Sai
Rek'Sai's base damage is high, along with a gap closer and a knockup she can easily find prey for the both of you. As well as her being a dive champion lantern can allow her to Void Rush (R) aggressively while having a way to get out.
Elise
Elise's setup guarantees hooks, but a mis-flay can make a cocoon miss more times than not. Otherwise her max health damage into execute damage makes ganking mid for her a queen's dream.
Lee Sin
Lee Sin can Safeguard (W) onto lanterns and can use Death Sentence/Flay for a Sonic Wave (Q) to hit no matter what. With his high base damage and early game sustain you can win early fights for scuttle with Lee almost any game that you play. Fabled legend tells of a lantern-sec where he jumps to lantern thrown behind the enemy into a Dragon's Rage (R) into The Box.
Poppy
Poppy being lanterned in and then being able to stop enemy dashes with her Steadfast Presence (W) while also being able to pin the enemy against a wall stunning them with Heroic Charge (E). With her Hammer Shock (Q) doing a considerable amount of damage early game.
Olaf
Olaf has an amazing time once he's on top of an enemy, flaying an enemy close and lanterning him close will allow him to have a hay-day with his early game damage.
Morgana
Albeit not picked much anymore, Morgana has terrific setup with Dark Binding (Q) that will make the enemy spend eternity wishing they didn't have to deal with this. As well as her Soul Shackles (R) are inescapable while the enemy is hooked.
Rengar
Rengar does immense amount damage when the enemy can't run away early. Lantern can pull Rengar into a bush so he is able to jump onto the enemy and Death Sentence guarantee's a full one shot combo from this ferocious feline.
Nocturne
Nocturne has his own engage with his Paranoia (R) and can fear enemies for a nightmarish combo of a Death Sentence into pure blender death.
Diana
Diana is capable of gap closing the enemy but does not have the damage early game to benefit off ganking Thresh, but once level 6 rolls around can use lantern engages for surprise moon ceremonies for the enemy.
Jarvan IV
J4 has some of the best setup in the game but does not have the damage to support it. Although he does not have amazing gank opportunity he does have amazing engage potential with his Cataclysm (R) without having to Flag n' Drag on his way over to the fight. Lantern for fights and he can make fights shaky for the enemy.
Fiddlesticks
Fiddlesticks early game isn't anything to write home about, but Terrify (Q) for a free fear can guarantee a Death Sentence onto the enemy while he drains them with a high burst of damage they cannot escape. Later on his Crowstorm (R) can be used in creative ways with Thresh. Crowstorm out of sight and then get dragged in with a lantern for the ultimate unexpected flank.
-Piece of Sheet can suck it.
Kayn
Kayn needs a longer lane to be able to make use of the crowd control Thresh has in his kit, but can use this as an opportunity to get orbs for his form pretty easily.
Nidalee
Nidalee can be a tricky cat to work with, especially since you can knock her out of her Javelin Toss (Q) with Flay and not even realize it. Albeit Death Sentence is capable of making cougar form do a lot of damage without a spear hitting.
Shaco
Shaco has his own way of getting in, but not really a way of getting out. Shaco Deceives (Q) in, Flay the enemy closer while he sets down a box and when they're feared Death Sentence allows the killer clown to get free backstabs onto the enemy.
Skarner
Skarner doesn't deal the necessary damage early game for Thresh's Crowd Control to really matter. Level 6 and beyond when Skarner can Impale (R) them towards an inevitable death towards The Box.
Viego
Viego is another champion that just doesn't deal enough damage to capitalize on Thresh's early game crowd control, but late game these two can be a menacing combo that will truly heartbreak the enemy.
Graves
Graves does not deal enough damage early game for ganks to matter. Later in the game, he can be a solid carry that you can capitalize on with lanterns to keep him safe.
Lillia
Lillia up until level 6 is incapable of ganking mid lane since she does not have the damage needed to even have a dream of killing the enemy.
Rammus
Rammus rolls on by not having enough damage to kill an enemy early game, but once you hit level 6 Rammus' taunt will allow a hook to land and make the enemy gasp in awe and only able to say "Ok"
Shyvana
Shyvana doesn't deal enough damage early game but level 6 and beyond her dragon form takes care of that entirely. Flay n Drag them through the fire for a nice crispy kill.
Ivern
No.
Why have an Ivern when you can have literally anything else, no damage, some setup but it's small.
Thresh Mid for Some Reason
Build Guide By Thresh Mid
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