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Warwick can be difficult to play against, he has passive priority in early game and can actually win 1v1 in late game, don't try to fight him alone. He can also cancel Zac's E with his fear, be careful.
Kayn
Kayn is very strong against tank and Zac is not different. Kayn has very sustain and damage, you can never trade with him. He can stop your E with his W if timed correctly.
Rek'Sai
His early game is godlike, arguably best early game of any jungler. He will try to invade you, don't let him invade you and you will oustcale him.
Udyr
Super annoying to fight, a lot of movement, and a lot of damage that can destroy you early.
Kha'Zix
Kha'zix can easly win early game if he counter jungles you. He has lots of damage early with his passive. Also, he can isolate Zac's passive and one shot each cell with Q.
Camille
Camille can easily kill Zac. She has a lot of true damage with her Q and can zone you easily aswell.
Vayne
Vayne is known to melt Tank, Zac is no exception. She can also dodge Zac's jump and even stop it with her E.
Thresh
Tresh can cancel Zac's jump with his E. Don't jump to the enemy ADC knowing that Tresh has his E ready.
Poppy
Poppy can stop Zac's jump. Don't try to jump her carries if she is with them. Especially when she's jungle she's hard to handle since she can countergank easily.
Master Yi
Nothing you can do against this guy in a 1v1 situation. In team fights you cancel him.
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