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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 3 Guides // Patch 25.18
10
144
Votes
3
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

The Most In-Depth Azir Guide Ever

Guide by Divine Azir updated September 10, 2025
  • In-depth
10
27
Votes
0
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.18] Victorious Twisted Fate Guide for Season 15 | Jammed

Guide by Jammed updated September 10, 2025
  • In-depth
9.8
4113
Votes
126
LoL Champion Vel'Koz Build Guide
LoL Champion Vel'Koz Build Guide

[Patch 25.18] SEASON 15 Azzapp's Guide To Vel'Koz [MID/APC/SUP]

Guide by Azzapp updated September 10, 2025
  • In-depth
9.2
225
Votes
21
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.18] PrestigeGalaxy's 5M+ Mastery Guide to Katarina! 🗡️

Guide by PrestigeGalaxy updated September 10, 2025
  • In-depth
8.9
870
Votes
50
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

❤ 🎶 [SEASON 16 NEW - 25.17 ] MASTER MID Seraphine! SEASON - THE SONG OF DEATH 🎶🎤

Guide by RezoneVerified updated September 10, 2025
  • In-depth
8.6
317
Votes
28
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[Patch 25.18] Hwei Season 15 Guide By Azzapp [Mid/APC/Sup]

Guide by Azzapp updated September 10, 2025
8.3
243
Votes
22
LoL Champion Aurelion Sol Build Guide
LoL Champion Aurelion Sol Build Guide

[Patch 25.18] SEASON 15 Aurelion Sol Guide by Azzapp

Guide by Azzapp updated September 10, 2025
2025, Season 3 Guides // Other Patches
10
240
Votes
15
LoL Champion Galio Build Guide
LoL Champion Galio Build Guide

[25.17] Hexeria's detailed Masters Guide to Galio

Guide by Hexeria updated September 8, 2025
  • In-depth
10
601
Votes
20
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Elite500, UNDISPUTED #1 VLAD PATCH 25.17

Guide by Elite500 updated September 8, 2025
  • In-depth
10
2327
Votes
159
LoL Champion Yasuo Build Guide
LoL Champion Yasuo Build Guide

[15.16] Tempest's Challenger Yasuo Guide [In-Depth]

Guide by WayOfTheTempesst updated August 29, 2025
  • In-depth
  • Stream
9.8
45
Votes
2
LoL Champion Aurelion Sol Build Guide
LoL Champion Aurelion Sol Build Guide

[Patch 25.17] Master OTP Season 15 Aurelion Sol Guide (+ Matchups Detail)

Guide by Event Horizon updated September 3, 2025
  • In-depth
9.8
247
Votes
6
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[25.17] Your True Colors - Complete Hwei Guide

Guide by Soft Headpats updated August 31, 2025
  • In-depth
9.8
171
Votes
8
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

[25.17] Anguishs GrandMasters Akali Mid/Top S15 Guide - Every Matchup/Item/Rune explained!

Guide by Anguish333 updated August 29, 2025
  • In-depth
9.8
2606
Votes
129
LoL Champion Yone Build Guide
LoL Champion Yone Build Guide

[15.17] Tempest's Challenger Yone Guide [In-Depth]

Guide by WayOfTheTempesst updated August 29, 2025
  • In-depth
  • Stream
9.8
832
Votes
54
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.17] Twisted Fate guide - Grandmaster, Halfhand 🥇

Guide by Halfhand updated August 28, 2025
  • In-depth
9.7
180
Votes
15
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[15.17] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.6
68
Votes
7
LoL Champion Aurora Build Guide
LoL Champion Aurora Build Guide

(25.17) ( ADVANCED COMBOS + UPDATED ) AURORA GUIDE : Aurora is one of the best champions to OTP in league ( MOST MASTERY POINTS EUNE )

Guide by AuroraAddict updated August 28, 2025
  • In-depth
9.6
96
Votes
5
LoL Champion Veigar Build Guide
LoL Champion Veigar Build Guide

Guide of an Veigar OTP star zall I Challenger Veigar OTP 1217 LP Peak I

Guide by star zall updated September 8, 2025
  • In-depth
9.5
591
Votes
36
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 16] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated September 8, 2025
  • In-depth
9.5
1989
Votes
128
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.17] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated September 2, 2025
1 2 3 4 5 6 7 8 29 50
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYunaraYuumiZacZedZeriZiggsZileanZoeZyra
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