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LoL Champion Build Guides: Cassiopeia

Cassiopeia RP Cost 880 Cassiopeia BE Cost4800
Pick 71%
Win 54%
Pick 15%
Win 54%
Pick 13%
Win 52%
Wishlist

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends Patch 10.16. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S10 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!


Season 10 Guides
LoL Champion Cassiopeia Build Guide

Yeager's Master Cassiopeia Guide

Guide by Yeager updated August 13, 2020
  • 10.16
  • In-depth
Votes: 808
Views: 2,246,189
LoL Champion Cassiopeia Build Guide

[Season 10, P.15] LinCassX Challenger Cassiopeia Guide

Guide by LinCass updated August 5, 2020
  • 10.16
  • In-depth
Votes: 48
Views: 38,104
LoL Champion Cassiopeia Build Guide

[10.16 Rezone's Indepth Midlane Cassiopeia SEASON 10!

Guide by RezoneVerified updated August 14, 2020
  • 10.16
  • In-depth
Votes: 118
Views: 377,605
LoL Champion Cassiopeia Build Guide

[10.16] Raen's Cassiopeia (°,,°) Tips & Build

Guide by Raen updated August 9, 2020
  • 10.16
Votes: 37
Views: 68,680
Season 10 Builds
LoL Champion Cassiopeia Build Guide

Cassiopeia Jesuscirraptor SUP

Build by Jesuscirraptor updated August 11, 2020
  • 10.16
Rating Pending
Views: 3,252
LoL Champion Cassiopeia Build Guide

The tankiopea

Build by SwrdMaster updated August 9, 2020
  • 10.16
New Build
Views: 568
LoL Champion Cassiopeia Build Guide

Cassiopeia Jesuscirraptor JG

Build by Jesuscirraptor updated August 11, 2020
  • 10.16
Rating Pending
Views: 2,511
LoL Champion Cassiopeia Build Guide

[10.16] The holy and blessed Cassiopeia guide!

Build by SnakeOnRiver updated August 13, 2020
  • 10.16
New Build
Views: 115
LoL Champion Cassiopeia Build Guide

Snek (Mid)

Build by ObserverOfTime updated August 13, 2020
  • 10.16
New Build
Views: 28
LoL Champion Cassiopeia Build Guide

cassiopiea jungle

Build by Guest updated July 27, 2020
  • 10.15
Rating Pending
Views: 793
LoL Champion Cassiopeia Build Guide

Cass Late game Carry

Build by smokiie updated July 21, 2020
  • 10.14
Rating Pending
Views: 17,998
LoL Champion Cassiopeia Build Guide

God Tier Cassiopeia

Build by ROFLMAOXD updated July 20, 2020
  • 10.14
Rating Pending
Views: 2,332
LoL Champion Cassiopeia Build Guide

Cassiopeia Mid (Conq)

Build by SaimonsJuniorLP updated July 14, 2020
  • 10.14
Rating Pending
Views: 690
LoL Champion Cassiopeia Build Guide

10.14 Cass Sup (Sleeprer)

Build by OmAEn updated July 10, 2020
  • 10.14
Rating Pending
Views: 2,191
LoL Champion Cassiopeia Build Guide

best cassio EUW insane stomping lane

Build by Erolle updated July 18, 2020
  • 10.14
Rating Pending
Views: 273
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by Majkyy updated July 18, 2020
  • 10.14
Rating Pending
Views: 374
LoL Champion Cassiopeia Build Guide

[10.12] - Annihilate Your Game With Cassiopeia

Build by LethalCassiopeia updated June 16, 2020
  • 10.12
Votes: 11
Views: 13,862
LoL Champion Cassiopeia Build Guide

Tank Cass

Build by Guest updated June 3, 2020
  • 10.11
Rating Pending
Views: 1,187
LoL Champion Cassiopeia Build Guide

[ 10.10 ] [ mid ] Cassiopeia

Build by Im uta updated May 15, 2020
  • 10.10
Rating Pending
Views: 1,620
LoL Champion Cassiopeia Build Guide

Forkos's Cassiopeia Guide

Build by Guest updated May 22, 2020
  • 10.10
Rating Pending
Views: 733
1 2 3 4 5 6 7 8 18 29

Cassiopeia Build Stats

Patch 10.16: 238537 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 51%

Win Rate 3756 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 72%

Win Rate 57 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Gathering Storm
Gathering Storm

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 50%

Win Rate 1287 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 8025 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 50%

Win Rate 3953 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 51%

Win Rate 1474 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 17034 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 54%

Win Rate 1303 Games

Sapphire Crystal Refillable Potion

Third Best

Cassiopeia's 3rd Best Starter Items 50%

Win Rate 1431 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 11159 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 55%

Win Rate 4238 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 55%

Win Rate 1340 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 70%

Win Rate 1611 Games

  • 1
  • 2
  • 3
Patch 10.16: 238533 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 65%

Win Rate 52 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 50%

Win Rate 395 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 51%

Win Rate 70 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Gathering Storm
Gathering Storm

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 50%

Win Rate 1635 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 53%

Win Rate 53 Games

Flash Barrier

Third Best

Cassiopeia's 3rd Best Summoner Spells 51%

Win Rate 190 Games

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 2707 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 52%

Win Rate 298 Games

Sapphire Crystal Refillable Potion

Third Best

Cassiopeia's 3rd Best Starter Items 50%

Win Rate 273 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 50%

Win Rate 1383 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 51%

Win Rate 456 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 49%

Win Rate 184 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 65%

Win Rate 298 Games

  • 1
  • 2
Patch 9.24: 1569873 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 63%

Win Rate 68 Games

  • 1
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Third Best

Cassiopeia's 3rd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 108 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 47%

Win Rate 449 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 46%

Win Rate 54 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 61%

Win Rate 74 Games

  • 1
  • 2
  • 3

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 509 Games

  • 1
  • 2

Second Best

Cassiopeia's 2nd Best Trinket 38%

Win Rate 213 Games

Warding Totem
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 65%

Win Rate 79 Games

  • 1

Cassiopeia Skins

Cassiopeia's Abilities

Ability Range Cost Cooldown
Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 60 / 70 / 80 / 90
3.5
Cassiopeia blasts an area with a delayed high damaging poison, dealing 75 / 110 / 145 / 180 / 215 (+90% of ability power) magic damage over 3 seconds and granting her 30 / 35 / 40 / 45 / 50% movement speed which decays over 3 seconds if she hits a champion.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 80 / 90 / 100 / 110
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom in an arc in front of her, leaving toxic clouds for 5 seconds. Enemies in the cloud take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are slowed by 40 / 50 / 60 / 70 / 80% (decays over the duration) and are grounded, prohibiting the use of movement abilities.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
50
0.75
Cassiopeia deals 48 (+4x champion level) (+10% of ability power) magic damage to her target.

If the target is poisoned, Twin Fang deals 10 / 30 / 50 / 70 / 90 (+60% of ability power) bonus magic damage and restores 12 / 14 / 16 / 18 / 20% of Cassiopeia's ability power to her as health. This heal is 75% less effective against minions and small monsters.

If Twin Fang kills a unit, its mana cost is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
825
100
120 / 100 / 80 / 80 / 80
Cassiopeia releases a swirl of magical energy from her eyes, dealing 150 / 250 / 350 (+50% of ability power) magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds, while enemies facing away are slowed by 40% for the same duration.

Questions About Cassiopeia

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