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LoL Champion Build Guides: Cassiopeia

Cassiopeia RP Cost 880 Cassiopeia BE Cost4800
Pick 78%
Win 53%
Pick 13%
Win 55%
Pick 9%
Win 58%
Wishlist

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends Patch 11.2. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S11 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!


Season 11 Guides
LoL Champion Cassiopeia Build Guide

Yeager's Master Cassiopeia Guide

Guide by Yeager updated January 21, 2021
  • 11.2
  • In-depth
Votes: 933
Views: 2,560,118
LoL Champion Cassiopeia Build Guide

[11.2] Raen's Cassiopeia (°,,°) Tips & Build

Guide by Raen updated January 23, 2021
  • 11.2
Votes: 51
Views: 197,257
LoL Champion Cassiopeia Build Guide

[11.2 Rezone's Indepth Midlane Cassiopeia SEASON 11!

Guide by RezoneVerified updated January 22, 2021
  • 11.2
  • In-depth
Votes: 167
Views: 554,031
LoL Champion Cassiopeia Build Guide

Hyrav's Challenger Rank 1 Cassiopeia Guide

Guide by Hyrav updated January 16, 2021
  • 11.1
  • In-depth
Votes: 110
Views: 113,343
LoL Champion Cassiopeia Build Guide

Ambitieux's Quick Guide to Diamond

Guide by Ambitieux updated January 13, 2021
  • 11.1
  • In-depth
  • Stream
Votes: 24
Views: 2,167
LoL Champion Cassiopeia Build Guide

Zethal | [S11] Detailed Early Game + Matchups Included

Guide by Zethal_Na updated December 28, 2020
  • 10.25
Votes: 8
Views: 10,066
LoL Champion Cassiopeia Build Guide

Cassiopeia Mid/Top guide S11

Guide by FoxyGrill updated December 17, 2020
  • 10.25
Rating Pending
Views: 3,203
LoL Champion Cassiopeia Build Guide

Sneak charmer

Guide by Glaceonlol updated January 5, 2021
  • 10.25
Rating Pending
Views: 213
LoL Champion Cassiopeia Build Guide

Cassiopeia mid

Guide by Guest updated December 14, 2020
  • 10.25
Rating Pending
Views: 579
LoL Champion Cassiopeia Build Guide

yer's Recommended botlane [s11 update]

Guide by yers updated December 2, 2020
  • 10.24
Rating Pending
Views: 6,924
LoL Champion Cassiopeia Build Guide

S11 Cassiopeia Build EUW GrandMaster

Guide by ZeMoller updated November 13, 2020
  • 10.23
Rating Pending
Views: 7,410
Season 11 Builds
LoL Champion Cassiopeia Build Guide

HOP LA J'AI DIS HOP LA

Build by Guest updated January 17, 2021
  • 11.1
New Build
Views: 168
LoL Champion Cassiopeia Build Guide

- Cassiopeia support- s11

Build by liciousity updated January 21, 2021
  • 11.2
New Build
Views: 254
LoL Champion Cassiopeia Build Guide

[S11/10.25] - Annihilate Your Game With Cassiopeia

Build by LethalCassiopeia updated December 10, 2020
  • 10.25
Votes: 13
Views: 24,455
LoL Champion Cassiopeia Build Guide

OTP CASSIOPIA RANKED ONE TRICK

Build by somacrus updated December 19, 2020
  • 10.25
Rating Pending
Views: 589
LoL Champion Cassiopeia Build Guide

Cassiopea full movement speed build

Build by Guest updated December 18, 2020
  • 10.25
Rating Pending
Views: 521
LoL Champion Cassiopeia Build Guide

Cassio 10.24 build (Updated)

Build by Shur1ken updated November 29, 2020
  • 10.24
Rating Pending
Views: 7,190
LoL Champion Cassiopeia Build Guide

Cassiopeia 10.24-10.25 (high dmg good hp and sustain)

Build by Erolle updated December 4, 2020
  • 10.24
Rating Pending
Views: 841
LoL Champion Cassiopeia Build Guide

[10.24] Imperial Cass

Build by LinhMiu updated November 29, 2020
  • 10.24
Rating Pending
Views: 921
LoL Champion Cassiopeia Build Guide

Cassiopeia Preseason Build Options

Build by EazyMoneySn1per updated November 16, 2020
  • 10.23
Rating Pending
Views: 1,426
1 2 3 4 5 6 7 8 20 32

Cassiopeia Build Stats

Patch 11.2: 108754 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 50%

Win Rate 2836 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 53%

Win Rate 1378 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 62%

Win Rate 143 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Gathering Storm
Gathering Storm

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 6252 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 50%

Win Rate 4644 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 49%

Win Rate 1962 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 50%

Win Rate 11615 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 10268 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 53%

Win Rate 4082 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 54%

Win Rate 1330 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 67%

Win Rate 1463 Games

  • 1
  • 2
  • 3
Patch 11.2: 108758 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 64%

Win Rate 56 Games

  • 1
  • 2
  • 3
Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Celerity
Celerity
LoL Rune: Scorch
Scorch

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 56%

Win Rate 108 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Gathering Storm
Gathering Storm

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 317 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 1481 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 63%

Win Rate 51 Games

Exhaust Flash

Third Best

Cassiopeia's 3rd Best Summoner Spells 55%

Win Rate 256 Games

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 52%

Win Rate 2031 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 51%

Win Rate 1349 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 53%

Win Rate 438 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 52%

Win Rate 174 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 70%

Win Rate 105 Games

  • 1
  • 2
Patch 11.2: 108765 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 63%

Win Rate 88 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 57%

Win Rate 115 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 379 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 53%

Win Rate 668 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 57%

Win Rate 192 Games

Exhaust Flash

Third Best

Cassiopeia's 3rd Best Summoner Spells 56%

Win Rate 95 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 54%

Win Rate 916 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 56%

Win Rate 499 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 51%

Win Rate 695 Games

Stealth Ward

Third Best

Cassiopeia's 3rd Best Trinket 49%

Win Rate 111 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 73%

Win Rate 60 Games

  • 1

Cassiopeia Skins

Cassiopeia's Abilities

Ability Range Cost Cooldown
Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 60 / 70 / 80 / 90
3.5
Cassiopeia blasts an area with a delayed high damaging poison, dealing 75 / 110 / 145 / 180 / 215 (+90% of ability power) magic damage over 3 seconds and granting her 30 / 35 / 40 / 45 / 50% movement speed which decays over 3 seconds if she hits a champion.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 80 / 90 / 100 / 110
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom in an arc in front of her, leaving toxic clouds for 5 seconds. Enemies in the cloud take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are slowed by 40 / 50 / 60 / 70 / 80% (decays over the duration) and are grounded, prohibiting the use of movement abilities.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
50
0.75
Cassiopeia deals 48 (+4x champion level) (+10% of ability power) magic damage to her target.

If the target is poisoned, Twin Fang deals 10 / 30 / 50 / 70 / 90 (+60% of ability power) bonus magic damage and restores 12 / 14 / 16 / 18 / 20% of Cassiopeia's ability power to her as health. This heal is 75% less effective against minions and small monsters.

If Twin Fang kills a unit, its mana cost is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
825
100
120 / 100 / 80 / 80 / 80
Cassiopeia releases a swirl of magical energy from her eyes, dealing 150 / 250 / 350 (+50% of ability power) magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds, while enemies facing away are slowed by 40% for the same duration.

Questions About Cassiopeia

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