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LoL Champion Build Guides: Cassiopeia

Cassiopeia RP Cost 880 Cassiopeia BE Cost4800
Pick 70%
Win 53%
Pick 15%
Win 53%
Pick 12%
Win 52%
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Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends Patch 10.16. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S10 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!


Season 10 Guides
LoL Champion Cassiopeia Build Guide

Yeager's Master Cassiopeia Guide

Guide by Yeager updated August 7, 2020
  • 10.16
  • In-depth
Votes: 797
Views: 2,216,627
LoL Champion Cassiopeia Build Guide

[Season 10, P.15] LinCassX Challenger Cassiopeia Guide

Guide by LinCass updated August 5, 2020
  • 10.16
  • In-depth
Votes: 44
Views: 34,942
LoL Champion Cassiopeia Build Guide

[10.16 Rezone's Indepth Midlane Cassiopeia SEASON 10!

Guide by RezoneVerified updated August 7, 2020
  • 10.16
  • In-depth
Votes: 118
Views: 374,800
LoL Champion Cassiopeia Build Guide

[10.16] Raen Cassiopeia (°,,°) Tips & Build

Guide by Raen updated August 5, 2020
  • 10.16
Votes: 36
Views: 65,155
Season 10 Builds
LoL Champion Cassiopeia Build Guide

cassiopiea jungle

Build by Guest updated July 27, 2020
  • 10.15
New Build
Views: 606
LoL Champion Cassiopeia Build Guide

Cass Late game Carry

Build by smokiie updated July 21, 2020
  • 10.14
Rating Pending
Views: 17,802
LoL Champion Cassiopeia Build Guide

God Tier Cassiopeia

Build by ROFLMAOXD updated July 20, 2020
  • 10.14
Rating Pending
Views: 1,805
LoL Champion Cassiopeia Build Guide

Cassiopeia Mid (Conq)

Build by SaimonsJuniorLP updated July 14, 2020
  • 10.14
Rating Pending
Views: 635
LoL Champion Cassiopeia Build Guide

10.14 Cass Sup (Sleeprer)

Build by OmAEn updated July 10, 2020
  • 10.14
Rating Pending
Views: 1,927
LoL Champion Cassiopeia Build Guide

best cassio EUW insane stomping lane

Build by Erolle updated July 18, 2020
  • 10.14
Rating Pending
Views: 227
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by Majkyy updated July 18, 2020
  • 10.14
Rating Pending
Views: 344
LoL Champion Cassiopeia Build Guide

[10.12] - Annihilate Your Game With Cassiopeia

Build by LethalCassiopeia updated June 16, 2020
  • 10.12
Votes: 10
Views: 13,535
LoL Champion Cassiopeia Build Guide

Tank Cass

Build by Guest updated June 3, 2020
  • 10.11
Rating Pending
Views: 1,139
LoL Champion Cassiopeia Build Guide

[ 10.10 ] [ mid ] Cassiopeia

Build by Im uta updated May 15, 2020
  • 10.10
Rating Pending
Views: 1,572
LoL Champion Cassiopeia Build Guide

Forkos's Cassiopeia Guide

Build by Guest updated May 22, 2020
  • 10.10
Rating Pending
Views: 718
LoL Champion Cassiopeia Build Guide

The Fat Snake - Cassiopeia Mid

Build by Guest updated April 29, 2020
  • 10.9
Rating Pending
Views: 2,120
LoL Champion Cassiopeia Build Guide

Totally a legit cassiopeia guide

Build by Craken18 updated May 4, 2020
  • 10.9
Rating Pending
Views: 862
LoL Champion Cassiopeia Build Guide

Cassiopeia SUP

Build by Jesuscirraptor updated April 28, 2020
  • 10.8
Rating Pending
Views: 3,014
LoL Champion Cassiopeia Build Guide

Cassiopeia JG

Build by Jesuscirraptor updated April 28, 2020
  • 10.8
Rating Pending
Views: 2,261
LoL Champion Cassiopeia Build Guide

cass supp

Build by Guest updated March 30, 2020
  • 10.6
Rating Pending
Views: 2,187
1 2 3 4 5 6 7 8 18 28

Cassiopeia Build Stats

Patch 10.16: 18609 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 52%

Win Rate 2627 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 60%

Win Rate 92 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Bloodline
Legend: Bloodline
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 584 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Gathering Storm
Gathering Storm

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 5483 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 50%

Win Rate 2669 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 52%

Win Rate 1031 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 11631 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 7690 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 55%

Win Rate 2876 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 56%

Win Rate 920 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 71%

Win Rate 1079 Games

  • 1
  • 2
  • 3
Patch 10.16: 18609 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 57%

Win Rate 54 Games

  • 1
  • 2
  • 3
Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Gathering Storm
Gathering Storm

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 50%

Win Rate 289 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 44%

Win Rate 153 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 49%

Win Rate 1094 Games

  • 1
  • 2

Second Best

Cassiopeia's 2nd Best Summoner Spells 49%

Win Rate 130 Games

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 50%

Win Rate 1853 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 53%

Win Rate 185 Games

Sapphire Crystal Refillable Potion

Third Best

Cassiopeia's 3rd Best Starter Items 53%

Win Rate 196 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 50%

Win Rate 945 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 50%

Win Rate 126 Games

Oracle Lens

Third Best

Cassiopeia's 3rd Best Trinket 48%

Win Rate 292 Games

Farsight Alteration
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 68%

Win Rate 56 Games

  • 1
  • 2
Patch 9.24: 1569873 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 63%

Win Rate 68 Games

  • 1
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Third Best

Cassiopeia's 3rd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 108 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 47%

Win Rate 449 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 46%

Win Rate 54 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 61%

Win Rate 74 Games

  • 1
  • 2
  • 3

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 509 Games

  • 1
  • 2

Second Best

Cassiopeia's 2nd Best Trinket 38%

Win Rate 213 Games

Warding Totem
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 65%

Win Rate 79 Games

  • 1

Cassiopeia Skins

Cassiopeia's Abilities

Ability Range Cost Cooldown
Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 60 / 70 / 80 / 90
3.5
Cassiopeia blasts an area with a delayed high damaging poison, dealing 75 / 110 / 145 / 180 / 215 (+90% of ability power) magic damage over 3 seconds and granting her 30 / 35 / 40 / 45 / 50% movement speed which decays over 3 seconds if she hits a champion.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 80 / 90 / 100 / 110
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom in an arc in front of her, leaving toxic clouds for 5 seconds. Enemies in the cloud take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are slowed by 40 / 50 / 60 / 70 / 80% (decays over the duration) and are grounded, prohibiting the use of movement abilities.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
50
0.75
Cassiopeia deals 48 (+4x champion level) (+10% of ability power) magic damage to her target.

If the target is poisoned, Twin Fang deals 10 / 30 / 50 / 70 / 90 (+60% of ability power) bonus magic damage and restores 12 / 14 / 16 / 18 / 20% of Cassiopeia's ability power to her as health. This heal is 75% less effective against minions and small monsters.

If Twin Fang kills a unit, its mana cost is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
825
100
120 / 100 / 80 / 80 / 80
Cassiopeia releases a swirl of magical energy from her eyes, dealing 150 / 250 / 350 (+50% of ability power) magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds, while enemies facing away are slowed by 40% for the same duration.

Questions About Cassiopeia

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