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LoL Champion Build Guides: Cassiopeia

Cassiopeia RP Cost 880 Cassiopeia BE Cost4800
Pick 81%
Win 49%
Pick 10%
Win 52%
Pick 8%
Win 50%
+ Wishlist

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends Patch 11.7. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S11 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!


Season 11 Guides
LoL Champion Cassiopeia Build Guide

Yeager's Master Cassiopeia Guide

Guide by Yeager updated March 31, 2021
  • 11.7
  • In-depth
Votes: 997
Views: 2,703,355
LoL Champion Cassiopeia Build Guide

Hyrav's Challenger Rank 1 Cassiopeia Guide

Guide by Hyrav updated April 1, 2021
  • 11.7
  • In-depth
Votes: 165
Views: 185,565
LoL Champion Cassiopeia Build Guide

[11.7 Rezone's Indepth Midlane Cassiopeia SEASON 11! The PO

Guide by RezoneVerified updated April 13, 2021
  • 11.7
  • In-depth
Votes: 184
Views: 572,106
LoL Champion Cassiopeia Build Guide

Raen's Cassiopeia (°,,°) Tips & Build

Guide by Raen updated April 5, 2021
  • 11.7
Votes: 54
Views: 218,693
LoL Champion Cassiopeia Build Guide

Zethal | [S11] Detailed Early Game + Matchups Included

Guide by Zethal_Na updated March 19, 2021
  • 11.6
Votes: 9
Views: 12,699
LoL Champion Cassiopeia Build Guide

Ambitieux's Quick Guide to Diamond

Guide by Ambitieux updated January 13, 2021
  • 11.1
  • In-depth
Votes: 28
Views: 4,508
LoL Champion Cassiopeia Build Guide

Cassiopeia Mid/Top guide S11

Guide by FoxyGrill updated December 17, 2020
  • 10.25
Rating Pending
Views: 7,417
LoL Champion Cassiopeia Build Guide

Sneak charmer

Guide by Glaceonlol updated January 5, 2021
  • 10.25
Rating Pending
Views: 1,072
LoL Champion Cassiopeia Build Guide

Cassiopeia mid

Guide by Guest updated December 14, 2020
  • 10.25
Rating Pending
Views: 1,204
LoL Champion Cassiopeia Build Guide

yer's Recommended botlane [s11 update]

Guide by yers updated December 2, 2020
  • 10.24
Votes: 6
Views: 9,897
LoL Champion Cassiopeia Build Guide

S11 Cassiopeia Build EUW GrandMaster

Guide by ZeMoller updated November 13, 2020
  • 10.23
Rating Pending
Views: 8,310
Season 11 Builds
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by AMohito updated April 10, 2021
  • 11.7
Rating Pending
Views: 395
LoL Champion Cassiopeia Build Guide

Cassiopeia, unrank to Challenger

Build by Guest updated April 4, 2021
  • 11.7
New Build
Views: 75
LoL Champion Cassiopeia Build Guide

Cassiopeia conq for all ranks op build

Build by worldgamer7 updated March 3, 2021
  • 11.5
Rating Pending
Views: 202
LoL Champion Cassiopeia Build Guide

Cassiopeia Jesuscirraptor SUP

Build by Jesuscirraptor updated February 7, 2021
  • 11.3
  • Off-Meta
Rating Pending
Views: 7,977
LoL Champion Cassiopeia Build Guide

[S11] Snek (Mid)

Build by ObserverOfTime updated February 3, 2021
  • 11.3
Rating Pending
Views: 7,482
LoL Champion Cassiopeia Build Guide

Cassiopeia Jesuscirraptor JG

Build by Jesuscirraptor updated February 2, 2021
  • 11.2
  • Off-Meta
Rating Pending
Views: 5,806
LoL Champion Cassiopeia Build Guide

Cassiopeia Guide

Build by Guest updated January 27, 2021
  • 11.2
Rating Pending
Views: 453
LoL Champion Cassiopeia Build Guide

Cassiopeia New Build

Build by Guest updated January 26, 2021
  • 11.2
  • Off-Meta
Rating Pending
Views: 329
LoL Champion Cassiopeia Build Guide

HOP LA J'AI DIS HOP LA

Build by Guest updated January 17, 2021
  • 11.1
Rating Pending
Views: 512
1 2 3 4 5 6 7 8 20 32

Cassiopeia Build Stats

Patch 11.7: 799748 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 49%

Win Rate 2842 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 49%

Win Rate 1438 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 657 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Scorch
Scorch

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 48%

Win Rate 7378 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 48%

Win Rate 5160 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 50%

Win Rate 2268 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 48%

Win Rate 13173 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 47%

Win Rate 10825 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 51%

Win Rate 5438 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 53%

Win Rate 1790 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 67%

Win Rate 1536 Games

  • 1
  • 2
  • 3
Patch 11.7: 799754 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 55%

Win Rate 75 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 52%

Win Rate 268 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 52%

Win Rate 60 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 49%

Win Rate 1491 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 59%

Win Rate 228 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 56%

Win Rate 52 Games

Flash Ghost

Cassiopeia's Starters

Cassiopeia's Best Starter Items 50%

Win Rate 2079 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 49%

Win Rate 581 Games

Doran's Ring Health Potion

Third Best

Cassiopeia's 3rd Best Starter Items 44%

Win Rate 96 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 1177 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 52%

Win Rate 580 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 53%

Win Rate 213 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 64%

Win Rate 270 Games

  • 1
  • 2
Patch 11.7: 799757 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 57%

Win Rate 115 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 51%

Win Rate 363 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 49%

Win Rate 55 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 48%

Win Rate 824 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 53%

Win Rate 245 Games

Exhaust Flash

Third Best

Cassiopeia's 3rd Best Summoner Spells 51%

Win Rate 213 Games

Flash Teleport

Cassiopeia's Starters

Cassiopeia's Best Starter Items 48%

Win Rate 1009 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 48%

Win Rate 807 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 49%

Win Rate 598 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 53%

Win Rate 160 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 65%

Win Rate 72 Games

  • 1

Cassiopeia Skins

Cassiopeia's Abilities

Ability Range Cost Cooldown
Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 60 / 70 / 80 / 90
3.5
Cassiopeia blasts an area with a delayed high damaging poison, dealing 75 / 110 / 145 / 180 / 215 (+90% of ability power) magic damage over 3 seconds and granting her 30 / 35 / 40 / 45 / 50% movement speed which decays over 3 seconds if she hits a champion.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 80 / 90 / 100 / 110
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom in an arc in front of her, leaving toxic clouds for 5 seconds. Enemies in the cloud take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are slowed by 40 / 50 / 60 / 70 / 80% (decays over the duration) and are grounded, prohibiting the use of movement abilities.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
50
0.75
Cassiopeia deals 48 (+4x champion level) (+10% of ability power) magic damage to her target.

If the target is poisoned, Twin Fang deals 10 / 30 / 50 / 70 / 90 (+60% of ability power) bonus magic damage and restores 12 / 14 / 16 / 18 / 20% of Cassiopeia's ability power to her as health. This heal is 75% less effective against minions and small monsters.

If Twin Fang kills a unit, its mana cost is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
825
100
120 / 100 / 80 / 80 / 80
Cassiopeia releases a swirl of magical energy from her eyes, dealing 150 / 250 / 350 (+50% of ability power) magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds, while enemies facing away are slowed by 40% for the same duration.

Questions About Cassiopeia

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