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LoL Champion Build Guides: Cassiopeia

Cassiopeia RP Cost 880 Cassiopeia BE Cost4800
Pick 75%
Win 52%
Pick 13%
Win 53%
Pick 11%
Win 50%
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Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends Patch 10.19. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S10 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!


Season 6 Builds
LoL Champion Cassiopeia Build Guide

The Sssnake [6.9]

Build by frotic updated May 7, 2016
  • 6.9
Rating Pending
Views: 5,954
LoL Champion Cassiopeia Build Guide

Casso Guide 6.9 Test

Build by The_Empathy updated May 5, 2016
  • 6.9
Rating Pending
Views: 10,469
LoL Champion Cassiopeia Build Guide

Road to Reworked Cassiopeia URF

Build by vitorbk updated May 13, 2016
  • 6.9
Rating Pending
Views: 15,922
LoL Champion Cassiopeia Build Guide

Build de Mulher

Build by vitorjua updated April 6, 2016
  • 6.7
Rating Pending
Views: 3,512
LoL Champion Cassiopeia Build Guide

[6.5] GG-NoRE Cassiopeia [Sustain 4 Days]

Build by DigitalAbsence updated March 11, 2016
  • 6.5
Rating Pending
Views: 7,342
LoL Champion Cassiopeia Build Guide

S6 VIPERINO TACTICIAN +80 WIN RATE

Build by heimeregen updated March 5, 2016
  • 6.4
Rating Pending
Views: 14,009
LoL Champion Cassiopeia Build Guide

cassiOPeia

Build by fabkuk69 updated March 2, 2016
  • 6.4
Rating Pending
Views: 2,370
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by chunhao updated February 7, 2016
  • 6.2
Rating Pending
Views: 7,483
LoL Champion Cassiopeia Build Guide

Poison hurts

Build by xXOvertakerXx updated December 11, 2015
  • 5.24
Rating Pending
Views: 35,223
Season 5 Guides
LoL Champion Cassiopeia Build Guide

Cassiopeia - The Nightmare Support [UPDATED PATCH 5.18]

Guide by lolmart updated September 19, 2015
  • 5.18
  • In-depth
Votes: 32
Views: 234,653
LoL Champion Cassiopeia Build Guide

Carry Games On Your Back

Guide by koyomilikesbloods updated September 24, 2015
  • 5.18
  • In-depth
Rating Pending
Views: 8,947
LoL Champion Cassiopeia Build Guide

[Diamond] A Descriptive Guide to Cassiopeia Top

Guide by Flexpoint updated June 28, 2015
  • 5.12
Rating Pending
Views: 19,457
LoL Champion Cassiopeia Build Guide

The proper way to play cassiopeia [Patch 5.11]

Guide by twist95 updated June 10, 2015
  • 5.11
  • In-depth
Rating Pending
Views: 44,791
LoL Champion Cassiopeia Build Guide

Cassiopeia Mid Lane - Season 5 (In depth)

Guide by GP Finn updated May 19, 2015
  • 5.9
  • In-depth
Rating Pending
Views: 174,618
LoL Champion Cassiopeia Build Guide

Snake Goddess [In-Depth]

Guide by Finkypop updated March 7, 2015
  • 5.4
  • In-depth
Votes: 40
Views: 1,018,159
LoL Champion Cassiopeia Build Guide

[Translation] In-depth guide of Cassiopeia by Fairy da yo

Guide by DRAVEWINDOT updated March 8, 2015
  • 5.4
  • In-depth
Votes: 11
Views: 194,045
LoL Champion Cassiopeia Build Guide

Cassiopeia - The AP 'ADC'

Guide by Blosb updated January 11, 2015
  • 4.21
Rating Pending
Views: 43,941
LoL Champion Cassiopeia Build Guide

[4.21] Cassiopeia Support, Let them be poked in cctyle

Guide by JoBilly updated December 15, 2014
  • 4.21
Rating Pending
Views: 29,284
LoL Champion Cassiopeia Build Guide

Tanky DPS Cassiopeia In-Depth Build

Guide by iPlato updated December 14, 2014
  • 4.21
Rating Pending
Views: 21,363
Season 5 Builds
LoL Champion Cassiopeia Build Guide

Cassiopeia bootless Top

Build by BlrdR3flX updated October 14, 2015
  • 5.20
Rating Pending
Views: 4,927

Cassiopeia Build Stats

Patch 10.19: 101805 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 51%

Win Rate 3109 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 51%

Win Rate 1493 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 65%

Win Rate 74 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 52%

Win Rate 7964 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 51%

Win Rate 4078 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 53%

Win Rate 1550 Games

Exhaust Flash

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 17130 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 53%

Win Rate 1608 Games

Sapphire Crystal Refillable Potion

Third Best

Cassiopeia's 3rd Best Starter Items 51%

Win Rate 1639 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 11259 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 55%

Win Rate 4518 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 56%

Win Rate 1431 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 68%

Win Rate 1693 Games

  • 1
  • 2
  • 3
Patch 10.19: 101826 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 54%

Win Rate 798 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 57%

Win Rate 121 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 56%

Win Rate 125 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 52%

Win Rate 1193 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 53%

Win Rate 603 Games

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 53%

Win Rate 373 Games

Exhaust Flash

Cassiopeia's Starters

Cassiopeia's Best Starter Items 52%

Win Rate 2220 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 53%

Win Rate 102 Games

Corrupting Potion

Third Best

Cassiopeia's 3rd Best Starter Items 50%

Win Rate 243 Games

Sapphire Crystal Refillable Potion

Trinket

Cassiopeia's Best Trinket 56%

Win Rate 919 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 50%

Win Rate 1511 Games

Warding Totem

Third Best

Cassiopeia's 3rd Best Trinket 54%

Win Rate 179 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 70%

Win Rate 136 Games

  • 1
Patch 10.19: 101835 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 61%

Win Rate 70 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 57%

Win Rate 63 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 109 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Gathering Storm
Gathering Storm

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 1807 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 60%

Win Rate 58 Games

Exhaust Flash

Third Best

Cassiopeia's 3rd Best Summoner Spells 58%

Win Rate 53 Games

Flash Ghost

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 2831 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 53%

Win Rate 373 Games

Sapphire Crystal Refillable Potion

Third Best

Cassiopeia's 3rd Best Starter Items 51%

Win Rate 342 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 51%

Win Rate 1540 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 51%

Win Rate 514 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 52%

Win Rate 185 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 77%

Win Rate 125 Games

  • 1
  • 2

Cassiopeia Skins

Cassiopeia's Abilities

Ability Range Cost Cooldown
Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 60 / 70 / 80 / 90
3.5
Cassiopeia blasts an area with a delayed high damaging poison, dealing 75 / 110 / 145 / 180 / 215 (+90% of ability power) magic damage over 3 seconds and granting her 30 / 35 / 40 / 45 / 50% movement speed which decays over 3 seconds if she hits a champion.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 80 / 90 / 100 / 110
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom in an arc in front of her, leaving toxic clouds for 5 seconds. Enemies in the cloud take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are slowed by 40 / 50 / 60 / 70 / 80% (decays over the duration) and are grounded, prohibiting the use of movement abilities.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
50
0.75
Cassiopeia deals 48 (+4x champion level) (+10% of ability power) magic damage to her target.

If the target is poisoned, Twin Fang deals 10 / 30 / 50 / 70 / 90 (+60% of ability power) bonus magic damage and restores 12 / 14 / 16 / 18 / 20% of Cassiopeia's ability power to her as health. This heal is 75% less effective against minions and small monsters.

If Twin Fang kills a unit, its mana cost is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
825
100
120 / 100 / 80 / 80 / 80
Cassiopeia releases a swirl of magical energy from her eyes, dealing 150 / 250 / 350 (+50% of ability power) magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds, while enemies facing away are slowed by 40% for the same duration.

Questions About Cassiopeia

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