Cassiopeia Build Guides, Runes and Items

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends S14 Patch 14.8. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S14 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!

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Cassiopeia Build & Runes

If you're looking for the best rune build for Cassiopeia we've got you covered. Below you can find the best items and runes to build for Cassiopeia, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Cassiopeia this is a great resource to quickly get a good rune selection for Patch 14.8. However, if you are a new Cassiopeia player we highly recommend reading through some of the guides above to learn why this build is strong on Cassiopeia!

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Our Stats Powered By

Patch 14.8: 21,257 matches scanned * Each section of the build is rated independently of the others

Precision

Sorcery

Second Best

50%

Win Rate 18% Pickrate

Sorcery

Precision

Third Best

49%

Win Rate 14% Pickrate

Precision

Resolve

Second Best

52%

Win Rate 10% Pickrate

Third Best

48%

Win Rate 6% Pickrate

Second Best

51%

Win Rate 23% Pickrate

Third Best

46%

Win Rate 0% Pickrate

Second Best

55%

Win Rate 14% Pickrate

Third Best

54%

Win Rate 9% Pickrate

Passive Ability

Second Best

54%

Win Rate 19% Pickrate

Passive Ability

Third Best

49%

Win Rate 6% Pickrate

Passive Ability

Our Stats Powered By

Patch 14.8: 21,257 matches scanned * Each section of the build is rated independently of the others

Precision

Sorcery

Second Best

52%

Win Rate 24% Pickrate

Sorcery

Precision

Third Best

48%

Win Rate 4% Pickrate

Precision

Resolve

Second Best

58%

Win Rate 7% Pickrate

Third Best

51%

Win Rate 3% Pickrate

Second Best

50%

Win Rate 25% Pickrate

Third Best

50%

Win Rate 0% Pickrate

Second Best

58%

Win Rate 13% Pickrate

Third Best

56%

Win Rate 10% Pickrate

Passive Ability

Second Best

54%

Win Rate 24% Pickrate

Passive Ability

Third Best

52%

Win Rate 11% Pickrate

Passive Ability

Our Stats Powered By

Patch 14.8: 21,257 matches scanned * Each section of the build is rated independently of the others

Precision

Sorcery

Second Best

50%

Win Rate 15% Pickrate

Precision

Inspiration

Third Best

49%

Win Rate 12% Pickrate

Sorcery

Precision

Second Best

51%

Win Rate 24% Pickrate

Third Best

55%

Win Rate 10% Pickrate

Second Best

50%

Win Rate 23% Pickrate

Third Best

56%

Win Rate 1% Pickrate

Second Best

59%

Win Rate 11% Pickrate

Third Best

56%

Win Rate 9% Pickrate

Passive Ability

Second Best

53%

Win Rate 16% Pickrate

Passive Ability

Third Best

49%

Win Rate 5% Pickrate

Passive Ability

Cassiopeia Counters

Learn Cassiopeia's counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Cassiopeia guides to see how to build and play against other champions you may find yourself up against!

This counter data is for Cassiopeia MIDDLE in Plat+ games. The percent shown is the enemy champion's counter rating against Cassiopeia. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.

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Counters powered by CounterStats

CR is Counter Rating, which is a combination of multiple counter factors. Counters shown are for Cassiopeia Cassiopeia MIDDLE

More Cassiopeia Counters

Cassiopeia Skins

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Find Cassiopeia's skins and when they were last on sale. Never miss a sale for your favorite skin by using our Wish List feature! You can also find all Cassiopeia skins and chromas on Cassiopeia's skins page.

Skin Release Wishlist Popularity Cost

Bewitching Cassiopeia

Special Events

October 20, 2022

+ Wishlist

1350

Coven Cassiopeia

August 12, 2021

+ Wishlist

1350

Spirit Blossom Cassiopeia

August 6, 2020

Wishlist

1350

Eternum Cassiopeia

September 21, 2017

+ Wishlist

1350

Jade Fang Cassiopeia

Special Events

February 8, 2013

+ Wishlist

975

Mythic Cassiopeia

July 19, 2012

+ Wishlist

975

Siren Cassiopeia

December 14, 2010

+ Wishlist

520

Desperada Cassiopeia

December 14, 2010

+ Wishlist

520

Classic Cassiopeia

Original

+ Wishlist

Cassiopeia's Abilities

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Serpentine Grace Cassiopeia's Passive

Self

Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.

Noxious Blast Cassiopeia's Q Ability

850

50 / 60 / 70 / 80 / 90

3.5

Cassiopeia blasts noxious gas, poisoning enemies and dealing 25 / 36.67 / 48.33 / 60 / 71.67 (+30% of ability power) magic damage over 3 seconds. Hitting a champion grants Cassiopeia 30 / 35 / 40 / 45 / 50% decaying over 3 seconds.

Miasma Cassiopeia's W Ability

700

70 / 80 / 90 / 100 / 110

24 / 22 / 20 / 18 / 16

Cassiopeia spews venom, leaving toxic clouds for 5 seconds. Enemies in the clouds take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are poisoned, grounded, and slowed by 40 / 50 / 60 / 70 / 80% for the same duration.

Twin Fang Cassiopeia's E Ability

700

50 / 48 / 46 / 44 / 42

0.75

Cassiopeia launches deadly fangs, dealing 52-120 (+10% of ability power) magic damage (depending on level). If the enemy is poisoned, they take an additional 20 / 40 / 60 / 80 / 100 (+60% of ability power) magic damage and Cassiopeia restores 10 / 11.5 / 13 / 14.5 / 16% ability power as health.

If this kills the target, this ability's cooldown is refunded.

Petrifying Gaze Cassiopeia's Ultimate (R) Ability

850

100

120 / 100 / 80 / 80 / 80

Cassiopeia unleashes a petrifying gaze, dealing 150 / 250 / 350 (+50% of ability power) magic damage and stunning enemies facing her for 2 seconds. Enemies facing away are slowed by 40% decaying over the same duration instead.

Questions About Cassiopeia

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Latest Questions

Feeling difficult to deal damage to mages who build RoA, what should I do?

Asked by kisred on May 11, 2016

Situation: In the early-mid game, I built Morellonomicon, opponent built RoA. Problem: Feeling difficult to deal damage to opponents who build RoA. As they have higher effective health after building RoA, I feel like 'my abilities do not...

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Which way is Katarina facing when she ults?

Asked by DJMurphster on August 31, 2015

If you need the enemy to be facing you for the Cassiopoia ult to be a stun, then which way is Katarina facing while she is ulting?

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Question on Cassiopeia

Asked by DJMurphster on June 23, 2015

I want to main Cassiopeia mid to climb the ladder, but i'm far from learning anything about her besides some combos. Should I just focus on tear for the majority of early, or is it better to constantly harass my opponent? What match-ups do I...

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Who should i choose?

Asked by misamon on June 6, 2015

???????????????????????? [b]Best Option[/b] ???????????????????????????????????????????? [color=#0080ff]Ahri , Cassiopeia , Diana , Ekko , Vladimir[/color]

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Who is the most OP champion in the game?

Asked by ProNinja19 on January 13, 2015

I am wondering who is the most OP champion to play. I wanna see how well I can do.

View (23) Answers

What are some fun or brainless champions?

Asked by CactusCarnivore on November 7, 2014

I have no idea who I should buy; any suggestions?

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Was Cassiopeia recently buffed?

Asked by wisso911 on November 6, 2014

Title.

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cassiopeia at bot lane

Asked by justhinking on October 14, 2014

has anyone tried to play cassiopeia at bot lane instead of an adc? as i don't main her nor am i at a high level of play i don't know how vibiable it can become. basicly here are some thoughts: 1. as an adc cass is a sustained damaged - low...

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Timing of a DoTs first "tick"

Asked by Teemoshy on July 8, 2014

So I wanted to ask this because I couldn't find it on LoLWiki. I've been under the impression that with DoTs the first tick of damage is done on application making it so that reapplying it in rapid succession will redo the first tick of damage....

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Lich bane Cass

Asked by Valkenhyn on May 13, 2013

So I've noticed that every time you use [[twin fang]] on Cass, you get an auto attack in between the .5 sec cooldowns. So i was wondering how she would fair with a [[lich bane]] as compared to other build options

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Next AP Mid to learn and why?

Asked by wtfproof on March 30, 2013

Hey, so I can't really decide which champion to learn next after I have finished with Evelynn. I play AP Mid in a fixed 5vs5 team so I need champions who are valuable in organised competitive play. Champions I currently am able to play on a decent...

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Cassiopeia Build Guides, Runes and Items

Cassiopeia The Serpent's Embrace

A can of Cass-whoopin

Cassiopeia S8 Top/Mid build

% 100 w rate Twisted Treeline Cass

S8 Cassiopeia Mid

Cassiopeia mid (New runes)

Nexz Cassiopeia Top and Mid in depth [Patch 7.23]

A complete and detailed guide to master the Snake (**WIP**)

Cassiopeia, The Sneaky Snakey SoloQ Monster

Took me to Master with Cassiopeia in S6, OTP Guide

Throwing A Mid Lane Hissy Fit

[7.17]"There is No Antidote for Me"

Cassiopeia Mid [S7]

CASSIOPEIA DEADLY BUILD