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LoL Champion Build Guides: Cassiopeia

Cassiopeia RP Cost 880 Cassiopeia BE Cost4800
Pick 81%
Win 51%
Pick 10%
Win 51%
Pick 9%
Win 51%
+ Wishlist

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends Patch 11.9. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S11 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!


Season 8 Builds
LoL Champion Cassiopeia Build Guide

Cassiopeia S8 Top/Mid build

Build by FireSkys22 updated January 29, 2018
  • 8.2
Rating Pending
Views: 24,208
LoL Champion Cassiopeia Build Guide

Season 8 Cassawin

Build by Guest updated January 6, 2018
  • 7.24
Rating Pending
Views: 6,528
LoL Champion Cassiopeia Build Guide

% 100 w rate Twisted Treeline Cass

Build by TRevvorT updated December 13, 2017
  • 7.24
Rating Pending
Views: 8,766
LoL Champion Cassiopeia Build Guide

S8 Cassiopeia Mid

Build by NTZL updated November 9, 2017
  • 7.22
Votes: 37
Views: 236,573
LoL Champion Cassiopeia Build Guide

Cassiopeia mid (New runes)

Build by Polsejensen updated November 11, 2017
  • 7.22
Votes: 6
Views: 65,988
LoL Champion Cassiopeia Build Guide

Nexz Cassiopeia Top and Mid in depth [Patch 7.23]

Build by Nexlovely updated November 20, 2017
  • 7.22
Rating Pending
Views: 43,950
LoL Champion Cassiopeia Build Guide

Snakerunes, Cassio after the Runes rework.

Build by Guest updated November 14, 2017
  • 7.22
Rating Pending
Views: 9,101
Season 7 Guides
LoL Champion Cassiopeia Build Guide

A complete and detailed guide to master the Snake (**WIP**)

Guide by Aminumbra updated August 1, 2017
  • 7.15
  • In-depth
Rating Pending
Views: 27,684
LoL Champion Cassiopeia Build Guide

Cassiopeia, The Sneaky Snakey SoloQ Monster

Guide by Collamis updated March 26, 2017
  • 7.6
Rating Pending
Views: 4,023
LoL Champion Cassiopeia Build Guide

Took me to Master with Cassiopeia in S6, OTP Guide

Guide by Corp Blue Cobra updated February 12, 2017
  • 7.3
Votes: 22
Views: 638,346
LoL Champion Cassiopeia Build Guide

Throwing A Mid Lane Hissy Fit

Guide by DeathWalker1 updated November 29, 2016
  • 6.23
Rating Pending
Views: 29,695
Season 7 Builds
LoL Champion Cassiopeia Build Guide

[7.17]"There is No Antidote for Me"

Build by Lincoln878 updated August 26, 2017
  • 7.17
Rating Pending
Views: 6,959
LoL Champion Cassiopeia Build Guide

This is a stupid idea

Build by Guest updated August 5, 2017
  • 7.15
Rating Pending
Views: 2,470
LoL Champion Cassiopeia Build Guide

Cassiopeia Mid [S7]

Build by WhichG updated July 16, 2017
  • 7.14
Rating Pending
Views: 5,485
LoL Champion Cassiopeia Build Guide

INSANE ONE SHOT CASSIOPEIA BUILD

Build by Zambs updated July 13, 2017
  • 7.14
Rating Pending
Views: 2,932
LoL Champion Cassiopeia Build Guide

CASSIOPEIA DEADLY BUILD

Build by HouYi updated July 8, 2017
  • 7.13
Rating Pending
Views: 2,652
LoL Champion Cassiopeia Build Guide

CASSIOPEIA TOP

Build by Guest updated June 24, 2017
  • 7.12
Rating Pending
Views: 2,765
LoL Champion Cassiopeia Build Guide

Cassiopeia Build

Build by Danny1819 updated April 19, 2017
  • 7.8
Rating Pending
Views: 2,306
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by Guest updated March 21, 2017
  • 7.6
Rating Pending
Views: 1,620
LoL Champion Cassiopeia Build Guide

BROKEN BUILD

Build by Frog Cake updated March 29, 2017
  • 7.6
Rating Pending
Views: 3,270

Cassiopeia Build Stats

Patch 11.9: 712639 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 49%

Win Rate 2647 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 53%

Win Rate 761 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 47%

Win Rate 1299 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 50%

Win Rate 6384 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 49%

Win Rate 4473 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 49%

Win Rate 1795 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 49%

Win Rate 11166 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 47%

Win Rate 9220 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 52%

Win Rate 4824 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 53%

Win Rate 1432 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 67%

Win Rate 1293 Games

  • 1
  • 2
  • 3
Patch 11.9: 712657 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 56%

Win Rate 146 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 57%

Win Rate 51 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 200 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 50%

Win Rate 1190 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 53%

Win Rate 73 Games

Flash Barrier

Third Best

Cassiopeia's 3rd Best Summoner Spells 51%

Win Rate 202 Games

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 49%

Win Rate 1680 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 56%

Win Rate 184 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 48%

Win Rate 958 Games

Stealth Ward

Third Best

Cassiopeia's 3rd Best Trinket 49%

Win Rate 461 Games

Farsight Alteration
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 66%

Win Rate 231 Games

  • 1
  • 2
Patch 11.9: 712660 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 56%

Win Rate 88 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 53%

Win Rate 293 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 55%

Win Rate 62 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 56%

Win Rate 79 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 54%

Win Rate 209 Games

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 50%

Win Rate 625 Games

Flash Heal

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 883 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 67%

Win Rate 112 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 52%

Win Rate 542 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 47%

Win Rate 742 Games

Stealth Ward
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 58%

Win Rate 64 Games

  • 1

Cassiopeia Skins

Cassiopeia's Abilities

Ability Range Cost Cooldown
Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 60 / 70 / 80 / 90
3.5
Cassiopeia blasts an area with a delayed high damaging poison, dealing 75 / 110 / 145 / 180 / 215 (+90% of ability power) magic damage over 3 seconds and granting her 30 / 35 / 40 / 45 / 50% movement speed which decays over 3 seconds if she hits a champion.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 80 / 90 / 100 / 110
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom in an arc in front of her, leaving toxic clouds for 5 seconds. Enemies in the cloud take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are slowed by 40 / 50 / 60 / 70 / 80% (decays over the duration) and are grounded, prohibiting the use of movement abilities.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
50 / 48 / 46 / 44 / 42
0.75
Cassiopeia deals 48 (+4x champion level) (+10% of ability power) magic damage to her target.

If the target is poisoned, Twin Fang deals 10 / 30 / 50 / 70 / 90 (+60% of ability power) bonus magic damage and restores 12 / 14 / 16 / 18 / 20% of Cassiopeia's ability power to her as health. This heal is 75% less effective against minions and small monsters.

If Twin Fang kills a unit, its mana cost is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
825
100
120 / 100 / 80 / 80 / 80
Cassiopeia releases a swirl of magical energy from her eyes, dealing 150 / 250 / 350 (+50% of ability power) magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds, while enemies facing away are slowed by 40% for the same duration.

Questions About Cassiopeia

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