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LoL Champion Build Guides: Cassiopeia

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends S11 Patch 11.15. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S11 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!

Season 2 Guides
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Carryopeia for Normals

Guide by TommyMann updated December 10, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

[IMPORTANT] The proper guide to Cassiopeia by Cacciopeia

Guide by Cacciopeia updated November 18, 2011
3.3
4
Votes
14
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia, the poisonous Snake [Ranked]

Guide by alex45696 updated December 2, 2012
Season 2 Builds
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Poisonous Passion

Build by STRiCHC0DE updated December 3, 2011
6.9
7
Votes
3
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia:Generic AP Build(up to date 9/13/2012)

Build by Th3Em0Sl4yer updated September 13, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

100% Legit Cassiopeia Speed snake throwing dominating guide

Build by lolobg123 updated November 10, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassy the gassy lassy

Build by Superhotfire3 updated December 3, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by Kapayaman updated August 23, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia ~ Queen Of the Poison

Build by Bleedzz updated August 18, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

The Wraithstealer

Build by Epicfeeder updated May 15, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

[German] Cassiopeia, die Schlange des Todes

Build by Warpstar95 updated May 10, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia - Ranked Game

Build by ZiolkoAndKamwii updated April 29, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by Wozny97 updated March 21, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia - The SpellWampQueen

Build by aalreit updated February 27, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

taste of TOXIN

Build by Baddox updated February 24, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

OUTPLAYED by Swift

Build by SwiftSolvang updated February 11, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

cassio cheat

Build by Guest updated February 8, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia build

Build by hammark9 updated January 22, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia look me in the eyes

Build by Guest updated January 15, 2012
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

ap / manassiopeia

Build by Guest updated January 14, 2012
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Cassiopeia Build & Runes

If you're looking for the best rune build for Cassiopeia we've got you covered. Below you can find the best items and runes to build for Cassiopeia, as determined by LeagueSpy's calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Cassiopeia this is a great resource to quickly get a good rune selection for Patch 11.15. However, if you are a new Cassiopeia player we highly recommend reading through some of the guides above to learn why this build is strong on Cassiopeia!

Patch 11.15: 242710 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Top Items

Cassiopeia's Runes

Cassiopeia's Best Runes 50%

Win Rate 2201 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 52%

Win Rate 1087 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 51%

Win Rate 814 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood
More Cassiopeia Runes

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 49%

Win Rate 5091 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 50%

Win Rate 3395 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 52%

Win Rate 2099 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 50%

Win Rate 9049 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 7328 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 51%

Win Rate 3751 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 52%

Win Rate 1447 Games

Oracle Lens
Don’t forget
to Buy Wards

Top Cassiopeia Players

Get match statisctics & builds Top Cassiopeia Players are using on LeagueSpy!

Patch 11.15: 242774 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Top Items

Cassiopeia's Runes

Cassiopeia's Best Runes 60%

Win Rate 87 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 54%

Win Rate 112 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 50%

Win Rate 328 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood
More Cassiopeia Runes

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 62%

Win Rate 76 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 59%

Win Rate 105 Games

Flash Barrier

Third Best

Cassiopeia's 3rd Best Summoner Spells 54%

Win Rate 255 Games

Exhaust Flash

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 711 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 56%

Win Rate 547 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 48%

Win Rate 607 Games

Stealth Ward

Third Best

Cassiopeia's 3rd Best Trinket 50%

Win Rate 114 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 74%

Win Rate 61 Games

  • 1

Top Cassiopeia Players

Get match statisctics & builds Top Cassiopeia Players are using on LeagueSpy!

Patch 11.15: 242750 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Top Items

Cassiopeia's Runes

Cassiopeia's Best Runes 57%

Win Rate 158 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 54%

Win Rate 71 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 50%

Win Rate 107 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood
More Cassiopeia Runes

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 61%

Win Rate 54 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 52%

Win Rate 1004 Games

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 53%

Win Rate 80 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 52%

Win Rate 1370 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 58%

Win Rate 377 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 49%

Win Rate 829 Games

Stealth Ward

Third Best

Cassiopeia's 3rd Best Trinket 51%

Win Rate 185 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 67%

Win Rate 196 Games

  • 1
  • 2

Top Cassiopeia Players

Get match statisctics & builds Top Cassiopeia Players are using on LeagueSpy!

Cassiopeia Counters

Learn 's counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Cassiopeia guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Cassiopeia Mid in Plat+ games. The percent shown is the enemy champion's counter rating against Cassiopeia. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.

Cassiopeia Skins

Cassiopeia's Abilities

Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 60 / 70 / 80 / 90
3.5
Cassiopeia blasts an area with a delayed high damaging poison, dealing 75 / 110 / 145 / 180 / 215 (+90% of ability power) magic damage over 3 seconds and granting her 30 / 35 / 40 / 45 / 50% movement speed which decays over 3 seconds if she hits a champion.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 80 / 90 / 100 / 110
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom in an arc in front of her, leaving toxic clouds for 5 seconds. Enemies in the cloud take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are slowed by 40 / 50 / 60 / 70 / 80% (decays over the duration) and are grounded, prohibiting the use of movement abilities.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
50 / 48 / 46 / 44 / 42
0.75
Cassiopeia deals 48 (+4x champion level) (+10% of ability power) magic damage to her target.

If the target is poisoned, Twin Fang deals 20 / 40 / 60 / 80 / 100 (+60% of ability power) bonus magic damage and restores 12 / 14 / 16 / 18 / 20% of Cassiopeia's ability power to her as health. This heal is 75% less effective against minions and small monsters.

If Twin Fang kills a unit, its mana cost is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
825
100
120 / 100 / 80 / 80 / 80
Cassiopeia releases a swirl of magical energy from her eyes, dealing 150 / 250 / 350 (+50% of ability power) magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds, while enemies facing away are slowed by 40% for the same duration.

Questions About Cassiopeia

Ask

Latest Questions

Feeling difficult to deal damage to mages who build RoA, what should I do?

Situation: In the early-mid game, I built Morellonomicon, opponent built RoA. Problem: Feeling difficult to deal damage to opponents who build RoA. As they have higher effective health after building RoA, I feel like 'my abilities do not...

View (4) Answers

Which way is Katarina facing when she ults?

If you need the enemy to be facing you for the Cassiopoia ult to be a stun, then which way is Katarina facing while she is ulting?

View (2) Answers

Question on Cassiopeia

I want to main Cassiopeia mid to climb the ladder, but i'm far from learning anything about her besides some combos. Should I just focus on tear for the majority of early, or is it better to constantly harass my opponent? What match-ups do I...

View (2) Answers

Who should i choose?

???????????????????????? [b]Best Option[/b] ???????????????????????????????????????????? [color=#0080ff]Ahri , Cassiopeia , Diana , Ekko , Vladimir[/color]

View (3) Answers

Who is the most OP champion in the game?

I am wondering who is the most OP champion to play. I wanna see how well I can do.

View (23) Answers

What are some fun or brainless champions?

I have no idea who I should buy; any suggestions?

View (8) Answers

Was Cassiopeia recently buffed?

Title.

View (1) Answers

cassiopeia at bot lane

has anyone tried to play cassiopeia at bot lane instead of an adc? as i don't main her nor am i at a high level of play i don't know how vibiable it can become. basicly here are some thoughts: 1. as an adc cass is a sustained damaged - low...

View (4) Answers

Timing of a DoTs first "tick"

So I wanted to ask this because I couldn't find it on LoLWiki. I've been under the impression that with DoTs the first tick of damage is done on application making it so that reapplying it in rapid succession will redo the first tick of damage....

View (0) Answers

Lich bane Cass

So I've noticed that every time you use [[twin fang]] on Cass, you get an auto attack in between the .5 sec cooldowns. So i was wondering how she would fair with a [[lich bane]] as compared to other build options

View (2) Answers

Next AP Mid to learn and why?

Hey, so I can't really decide which champion to learn next after I have finished with Evelynn. I play AP Mid in a fixed 5vs5 team so I need champions who are valuable in organised competitive play. Champions I currently am able to play on a decent...

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