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LoL Champion Build Guides: Cassiopeia

Cassiopeia RP Cost 880 Cassiopeia BE Cost4800
Pick 76%
Win 52%
Pick 13%
Win 52%
Pick 11%
Win 50%
Wishlist

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends Patch 10.19. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S10 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!


Season 2 Builds
LoL Champion Cassiopeia Build Guide

AGRESSIVE CASSIOPEIA

Build by ianaranega updated November 8, 2012
  • Shadow Isles
Rating Pending
Views: 1,085
LoL Champion Cassiopeia Build Guide

cassio mid lane

Build by snowers updated November 6, 2012
  • Shadow Isles
Rating Pending
Views: 945
LoL Champion Cassiopeia Build Guide

Cassiopeia personal build.

Build by Guest updated November 4, 2012
  • Shadow Isles
Rating Pending
Views: 880
LoL Champion Cassiopeia Build Guide

My Build for Cassiopeia

Build by JaSx17 updated November 4, 2012
  • Shadow Isles
Rating Pending
Views: 809
LoL Champion Cassiopeia Build Guide

III - The Empress

Build by Dawnemerald updated November 1, 2012
  • Shadow Isles
Rating Pending
Views: 1,190
LoL Champion Cassiopeia Build Guide

#Cassiopeia (AP) mid'

Build by Paxi updated October 22, 2012
  • Late September
Rating Pending
Views: 3,262
LoL Champion Cassiopeia Build Guide

Oskoff's Guide to Cassiopeia

Build by Guest updated October 14, 2012
  • Late September
Rating Pending
Views: 1,197
LoL Champion Cassiopeia Build Guide

Cassiopeia - [Mid]

Build by MiD Fukuu updated October 11, 2012
  • Late September
Rating Pending
Views: 2,766
LoL Champion Cassiopeia Build Guide

Cassiopeia - [Mid]

Build by Top Fukuu updated October 5, 2012
  • Late September
Rating Pending
Views: 1,917
LoL Champion Cassiopeia Build Guide

Cassiopeia: Amateur build

Build by Guest updated October 3, 2012
  • Late September
Rating Pending
Views: 1,522
LoL Champion Cassiopeia Build Guide

Cassiopeia The Serpent of Chaos

Build by FabricioBahia updated September 9, 2012
  • Late Agust
Rating Pending
Views: 1,331
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by zalvation updated September 2, 2012
  • Late Agust
Rating Pending
Views: 1,101
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by erikigus updated September 1, 2012
  • Late Agust
Rating Pending
Views: 899
LoL Champion Cassiopeia Build Guide

CASSIOPEA-HERE SNAKY SNAKY SNAKY- ap/MID

Build by SnOoOpKo updated August 27, 2012
  • Mid Agust
Rating Pending
Views: 1,612
LoL Champion Cassiopeia Build Guide

Sweet Snake

Build by LegendaryPotato updated August 26, 2012
  • Mid Agust
Rating Pending
Views: 873
LoL Champion Cassiopeia Build Guide

Cassiopeia - The Serpent's Embrace

Build by Guest updated August 20, 2012
  • Mid Agust
Rating Pending
Views: 1,398
LoL Champion Cassiopeia Build Guide

op cass

Build by Guest updated August 17, 2012
  • Mid Agust
Rating Pending
Views: 1,246
LoL Champion Cassiopeia Build Guide

Cassio

Build by iBreakd0wn updated August 15, 2012
  • Mid Agust
Rating Pending
Views: 1,213
LoL Champion Cassiopeia Build Guide

Cassio Ownage by Chiken

Build by Guest updated August 12, 2012
  • Early August
Rating Pending
Views: 1,023
LoL Champion Cassiopeia Build Guide

Cassiopeia: the medusa

Build by xx rafa xpertxx updated August 6, 2012
  • Early August
Rating Pending
Views: 1,914

Cassiopeia Build Stats

Patch 10.19: 276157 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 51%

Win Rate 3717 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 51%

Win Rate 1734 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 67%

Win Rate 84 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 9501 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 51%

Win Rate 4942 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 53%

Win Rate 1857 Games

Exhaust Flash

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 20496 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 53%

Win Rate 1906 Games

Sapphire Crystal Refillable Potion

Third Best

Cassiopeia's 3rd Best Starter Items 51%

Win Rate 1983 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 50%

Win Rate 13503 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 54%

Win Rate 5430 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 56%

Win Rate 1695 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 68%

Win Rate 2035 Games

  • 1
  • 2
  • 3
Patch 10.19: 276171 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 54%

Win Rate 956 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 57%

Win Rate 145 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 55%

Win Rate 153 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 52%

Win Rate 1396 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 54%

Win Rate 712 Games

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 51%

Win Rate 436 Games

Exhaust Flash

Cassiopeia's Starters

Cassiopeia's Best Starter Items 52%

Win Rate 2606 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 52%

Win Rate 285 Games

Sapphire Crystal Refillable Potion

Third Best

Cassiopeia's 3rd Best Starter Items 52%

Win Rate 131 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 56%

Win Rate 1068 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 49%

Win Rate 1789 Games

Warding Totem

Third Best

Cassiopeia's 3rd Best Trinket 54%

Win Rate 213 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 72%

Win Rate 163 Games

  • 1
Patch 10.19: 276179 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 61%

Win Rate 92 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Second Best

Cassiopeia's 2nd Best Runes 57%

Win Rate 82 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Third Best

Cassiopeia's 3rd Best Runes 57%

Win Rate 53 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Gathering Storm
Gathering Storm

Domination
LoL Path: Domination
LoL Rune: Ravenous Hunter
Ravenous Hunter
LoL Rune: Taste of Blood
Taste of Blood

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 2148 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 56%

Win Rate 68 Games

Exhaust Flash

Third Best

Cassiopeia's 3rd Best Summoner Spells 55%

Win Rate 67 Games

Flash Ghost

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 3375 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Starter Items 53%

Win Rate 443 Games

Sapphire Crystal Refillable Potion

Third Best

Cassiopeia's 3rd Best Starter Items 51%

Win Rate 399 Games

Corrupting Potion

Trinket

Cassiopeia's Best Trinket 50%

Win Rate 1847 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 52%

Win Rate 593 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 53%

Win Rate 221 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 75%

Win Rate 150 Games

  • 1
  • 2

Cassiopeia Skins

Cassiopeia's Abilities

Ability Range Cost Cooldown
Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 60 / 70 / 80 / 90
3.5
Cassiopeia blasts an area with a delayed high damaging poison, dealing 75 / 110 / 145 / 180 / 215 (+90% of ability power) magic damage over 3 seconds and granting her 30 / 35 / 40 / 45 / 50% movement speed which decays over 3 seconds if she hits a champion.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 80 / 90 / 100 / 110
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom in an arc in front of her, leaving toxic clouds for 5 seconds. Enemies in the cloud take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are slowed by 40 / 50 / 60 / 70 / 80% (decays over the duration) and are grounded, prohibiting the use of movement abilities.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
50
0.75
Cassiopeia deals 48 (+4x champion level) (+10% of ability power) magic damage to her target.

If the target is poisoned, Twin Fang deals 10 / 30 / 50 / 70 / 90 (+60% of ability power) bonus magic damage and restores 12 / 14 / 16 / 18 / 20% of Cassiopeia's ability power to her as health. This heal is 75% less effective against minions and small monsters.

If Twin Fang kills a unit, its mana cost is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
825
100
120 / 100 / 80 / 80 / 80
Cassiopeia releases a swirl of magical energy from her eyes, dealing 150 / 250 / 350 (+50% of ability power) magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds, while enemies facing away are slowed by 40% for the same duration.

Questions About Cassiopeia

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