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Cassiopeia Build Guides, Runes and Items
Cassiopeia The Serpent's Embrace
Find the best Cassiopeia build guides for League of Legends S13 Patch 13.6. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S13 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!
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AP Carry Cassiopeia
AP Carry Cassiopeia
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[7.17]"There is No Antidote for Me"
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This is a stupid idea
Cassiopeia Mid [S7]
CASSIOPEIA DEADLY BUILD
CASSIOPEIA TOP
Cassiopeia Build
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Cassiopeia
S7 New build CASSIOPEIA
The snake without an antidote
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CASSIOPEIA HEALING GUIDE
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Cassiopeia 1v9
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main cassiopeia guide
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Who needs boots?
BROKEN BUILD
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Am I Getting Under Your Skin? - Marksman APC Cassiopeia
Am I Getting Under Your Skin? - Marksman APC Cassiopeia
[6.9] Cassiopeia: The MarksMage
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The Serpent's Embrace:Tanky Mage Cassiopeia (Quick Guide)
Patch 6:13 Cassiopeia TOP/MID Guide
Season 6 In-Depth Cassiopeia Mid lane Guide
Cassiopeia Build & Runes
If you're looking for the best rune build for Cassiopeia we've got you covered. Below you can find the best items and runes to build for Cassiopeia, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Cassiopeia this is a great resource to quickly get a good rune selection for Patch 13.6. However, if you are a new Cassiopeia player we highly recommend reading through some of the guides above to learn why this build is strong on Cassiopeia!
* Each section of the build is rated independently of the others
Cassiopeia's Runes
51%
Win Rate 21724 Games
- 1
- 2
- 3
Second Best
53%
Win Rate 5491 Games
Third Best
52%
Win Rate 4122 Games
Cassiopeia's Summoner Spells
52%
Win Rate 32647 Games
- 1
- 2
- 3
Cassiopeia's Starters
52%
Win Rate 131162 Games
- 1
- 2
Trinket
57%
Win Rate 12704 Games
- 1
- 2
- 3
Second Best
55%
Win Rate 18303 Games
Farsight Alteration
Third Best
48%
Win Rate 24579 Games
Stealth Ward
Don’t forgetto Buy Wards
Mythic
Cassiopeia's Core Items
Cassiopeia's Luxury Items
Cassiopeia's Ability Order
66%
Win Rate 22808 Games
- 1
- 2
- 3
Serpentine Grace (PASSIVE)
Passive Ability
Second Best
68%
Win Rate 5305 Games
Serpentine Grace (PASSIVE)
Passive Ability
Third Best
66%
Win Rate 1472 Games
Serpentine Grace (PASSIVE)
Passive Ability
* Each section of the build is rated independently of the others
Cassiopeia's Runes
54%
Win Rate 3242 Games
- 1
- 2
- 3
Second Best
53%
Win Rate 1572 Games
Third Best
59%
Win Rate 956 Games
Cassiopeia's Summoner Spells
54%
Win Rate 8562 Games
- 1
- 2
- 3
Cassiopeia's Starters
53%
Win Rate 23442 Games
- 1
- 2
Trinket
50%
Win Rate 5173 Games
- 1
- 2
- 3
Second Best
56%
Win Rate 3186 Games
Farsight Alteration
Third Best
59%
Win Rate 2572 Games
Oracle Lens
Don’t forgetto Buy Wards
Mythic
Cassiopeia's Core Items
Cassiopeia's Luxury Items
Cassiopeia's Ability Order
64%
Win Rate 4160 Games
- 1
- 2
- 3
Serpentine Grace (PASSIVE)
Passive Ability
Second Best
65%
Win Rate 1359 Games
Serpentine Grace (PASSIVE)
Passive Ability
Third Best
71%
Win Rate 266 Games
Serpentine Grace (PASSIVE)
Passive Ability
* Each section of the build is rated independently of the others
Cassiopeia's Runes
53%
Win Rate 995 Games
- 1
- 2
- 3
Second Best
62%
Win Rate 53 Games
Third Best
61%
Win Rate 162 Games
Cassiopeia's Summoner Spells
53%
Win Rate 746 Games
- 1
- 2
- 3
Cassiopeia's Starters
53%
Win Rate 7396 Games
- 1
- 2
Trinket
54%
Win Rate 1491 Games
- 1
- 2
- 3
Second Best
60%
Win Rate 555 Games
Oracle Lens
Third Best
48%
Win Rate 1384 Games
Stealth Ward
Don’t forgetto Buy Wards
Mythic
Cassiopeia's Core Items
Cassiopeia's Luxury Items
Cassiopeia's Ability Order
63%
Win Rate 736 Games
- 1
- 2
Serpentine Grace (PASSIVE)
Passive Ability
Second Best
68%
Win Rate 144 Games
Serpentine Grace (PASSIVE)
Passive Ability
Cassiopeia Counters
Learn Cassiopeia's counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Cassiopeia guides to see how to build and play against other champions you may find yourself up against!
This counter data is for Cassiopeia Mid in Plat+ games. The percent shown is the enemy champion's counter rating against Cassiopeia. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.
Best Against Cassiopeia
Worst Against Cassiopeia
Cassiopeia Skins
Find Cassiopeia's skins and when they were last on sale. Never miss a sale for your favorite skin by using our Wish List feature! You can also find all Cassiopeia skins and chromas on Cassiopeia's skins page.
Wishlist
Our Wish List feature will send you notifications when your skins are on sale!Cassiopeia's Abilities
If this kills the target, this ability's cooldown is refunded.
Questions About Cassiopeia
Latest Questions
Feeling difficult to deal damage to mages who build RoA, what should I do?
Situation: In the early-mid game, I built Morellonomicon, opponent built RoA. Problem: Feeling difficult to deal damage to opponents who build RoA. As they have higher effective health after building RoA, I feel like 'my abilities do not...
Which way is Katarina facing when she ults?
If you need the enemy to be facing you for the Cassiopoia ult to be a stun, then which way is Katarina facing while she is ulting?
Question on Cassiopeia
I want to main Cassiopeia mid to climb the ladder, but i'm far from learning anything about her besides some combos. Should I just focus on tear for the majority of early, or is it better to constantly harass my opponent? What match-ups do I...
Who should i choose?
???????????????????????? [b]Best Option[/b] ???????????????????????????????????????????? [color=#0080ff]Ahri , Cassiopeia , Diana , Ekko , Vladimir[/color]
Who is the most OP champion in the game?
I am wondering who is the most OP champion to play. I wanna see how well I can do.
What are some fun or brainless champions?
I have no idea who I should buy; any suggestions?
Was Cassiopeia recently buffed?
Title.
cassiopeia at bot lane
has anyone tried to play cassiopeia at bot lane instead of an adc? as i don't main her nor am i at a high level of play i don't know how vibiable it can become. basicly here are some thoughts: 1. as an adc cass is a sustained damaged - low...
Timing of a DoTs first "tick"
So I wanted to ask this because I couldn't find it on LoLWiki. I've been under the impression that with DoTs the first tick of damage is done on application making it so that reapplying it in rapid succession will redo the first tick of damage....
Lich bane Cass
So I've noticed that every time you use [[twin fang]] on Cass, you get an auto attack in between the .5 sec cooldowns. So i was wondering how she would fair with a [[lich bane]] as compared to other build options
Next AP Mid to learn and why?
Hey, so I can't really decide which champion to learn next after I have finished with Evelynn. I play AP Mid in a fixed 5vs5 team so I need champions who are valuable in organised competitive play. Champions I currently am able to play on a decent...
