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Cassiopeia Build Guides, Runes and Items

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends S13 Patch 13.1. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S13 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!

Season 11 Builds
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

HOP LA J'AI DIS HOP LA

Build by Guest updated January 17, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Untouchable

Build by Haamiah38 updated October 12, 2021
  • Off-Meta
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopea full movement speed build

Build by Guest updated December 18, 2020
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

[S11] Snek (Mid)

Build by ObserverOfTime updated February 3, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

OTP CASSIOPIA RANKED ONE TRICK

Build by somacrus updated December 19, 2020
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia 10.24-10.25 (high dmg good hp and sustain)

Build by Erolle updated December 4, 2020
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia 11.21 build

Build by Guest updated October 20, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

11.20 The Ultimate Guide to Cassiopeia

Build by KeNaNFoR updated October 11, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Self Guide

Build by TalentNotThere updated September 12, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Jesucirraptor MID The Fast

Build by Jesuscirraptor updated August 23, 2021
  • Off-Meta
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Tank Cassio Support WIP

Build by Dramaddox101 updated July 29, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopiea fast carry

Build by ASTRO1 updated May 30, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Tenta isso

Build by Guest updated May 25, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassio Build

Build by Ktibor0807 updated April 16, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia, unrank to Challenger

Build by Guest updated April 4, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia conq for all ranks op build

Build by worldgamer7 updated March 3, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Guide

Build by Guest updated January 27, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia New Build

Build by Guest updated January 26, 2021
  • Off-Meta
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

- Cassiopeia support- s11

Build by liciousity updated January 21, 2021
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

[10.24] Imperial Cass

Build by LinhMiu updated November 29, 2020
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Cassiopeia Build & Runes

If you're looking for the best rune build for Cassiopeia we've got you covered. Below you can find the best items and runes to build for Cassiopeia, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Cassiopeia this is a great resource to quickly get a good rune selection for Patch 13.1. However, if you are a new Cassiopeia player we highly recommend reading through some of the guides above to learn why this build is strong on Cassiopeia!

Patch 13.1: 644330 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 50%

Win Rate 9022 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Sorcery
LoL Path: Sorcery
LoL Rune: Transcendence
Transcendence
LoL Rune: Manaflow Band
Manaflow Band

Second Best

Cassiopeia's 2nd Best Runes 49%

Win Rate 2721 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Resolve
LoL Path: Resolve
LoL Rune: Conditioning
Conditioning
LoL Rune: Overgrowth
Overgrowth

Third Best

Cassiopeia's 3rd Best Runes 50%

Win Rate 2428 Games

Sorcery
LoL Path: Sorcery
LoL Rune: Phase Rush
Phase Rush
LoL Rune: Manaflow Band
Manaflow Band
LoL Rune: Transcendence
Transcendence
LoL Rune: Scorch
Scorch

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 50%

Win Rate 12114 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 50%

Win Rate 7819 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 52%

Win Rate 2978 Games

Flash Ghost

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 21015 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 48%

Win Rate 16045 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 54%

Win Rate 8605 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 54%

Win Rate 2943 Games

Oracle Lens
Don’t forget
to Buy Wards
Patch 13.1: 644333 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 51%

Win Rate 704 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Sorcery
LoL Path: Sorcery
LoL Rune: Transcendence
Transcendence
LoL Rune: Manaflow Band
Manaflow Band

Second Best

Cassiopeia's 2nd Best Runes 53%

Win Rate 169 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Resolve
LoL Path: Resolve
LoL Rune: Conditioning
Conditioning
LoL Rune: Overgrowth
Overgrowth

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 84 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Sorcery
LoL Path: Sorcery
LoL Rune: Transcendence
Transcendence
LoL Rune: Manaflow Band
Manaflow Band

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 50%

Win Rate 2270 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 51%

Win Rate 850 Games

Flash Ignite

Third Best

Cassiopeia's 3rd Best Summoner Spells 52%

Win Rate 167 Games

Flash Barrier

Cassiopeia's Starters

Cassiopeia's Best Starter Items 50%

Win Rate 3130 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 47%

Win Rate 2309 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 54%

Win Rate 1216 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 56%

Win Rate 560 Games

Oracle Lens
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 61%

Win Rate 628 Games

  • 1
  • 2
Patch 12.22: 171634 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 47%

Win Rate 109 Games

  • 1
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Sorcery
LoL Path: Sorcery
LoL Rune: Transcendence
Transcendence
LoL Rune: Manaflow Band
Manaflow Band

Second Best

Cassiopeia's 2nd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Third Best

Cassiopeia's 3rd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 59%

Win Rate 123 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 53%

Win Rate 81 Games

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 53%

Win Rate 62 Games

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 0%

Win Rate Games

! Small Sample Size Warning * There is either not a lot of games played on this champion or the builds vary greatly, we have provided the top build but it does not have a high confidence rating so use your own discretion.

Trinket

Cassiopeia's Best Trinket 60%

Win Rate 227 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 52%

Win Rate 67 Games

Oracle Lens

Third Best

Cassiopeia's 3rd Best Trinket 47%

Win Rate 315 Games

Stealth Ward
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 0%

Win Rate Games

  • 1
! Small Sample Size Warning * There is either not a lot of games played on this champion or the builds vary greatly, we have provided the top build but it does not have a high confidence rating so use your own discretion.

Cassiopeia Counters

Learn Cassiopeia's counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Cassiopeia guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Cassiopeia Mid in Plat+ games. The percent shown is the enemy champion's counter rating against Cassiopeia. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.

Cassiopeia Skins

Cassiopeia's Abilities

Questions About Cassiopeia

Ask

Latest Questions

Feeling difficult to deal damage to mages who build RoA, what should I do?

Situation: In the early-mid game, I built Morellonomicon, opponent built RoA. Problem: Feeling difficult to deal damage to opponents who build RoA. As they have higher effective health after building RoA, I feel like 'my abilities do not...

View (4) Answers

Which way is Katarina facing when she ults?

If you need the enemy to be facing you for the Cassiopoia ult to be a stun, then which way is Katarina facing while she is ulting?

View (2) Answers

Question on Cassiopeia

I want to main Cassiopeia mid to climb the ladder, but i'm far from learning anything about her besides some combos. Should I just focus on tear for the majority of early, or is it better to constantly harass my opponent? What match-ups do I...

View (2) Answers

Who should i choose?

???????????????????????? [b]Best Option[/b] ???????????????????????????????????????????? [color=#0080ff]Ahri , Cassiopeia , Diana , Ekko , Vladimir[/color]

View (3) Answers

Who is the most OP champion in the game?

I am wondering who is the most OP champion to play. I wanna see how well I can do.

View (23) Answers

What are some fun or brainless champions?

I have no idea who I should buy; any suggestions?

View (8) Answers

Was Cassiopeia recently buffed?

Title.

View (1) Answers

cassiopeia at bot lane

has anyone tried to play cassiopeia at bot lane instead of an adc? as i don't main her nor am i at a high level of play i don't know how vibiable it can become. basicly here are some thoughts: 1. as an adc cass is a sustained damaged - low...

View (4) Answers

Timing of a DoTs first "tick"

So I wanted to ask this because I couldn't find it on LoLWiki. I've been under the impression that with DoTs the first tick of damage is done on application making it so that reapplying it in rapid succession will redo the first tick of damage....

View (0) Answers

Lich bane Cass

So I've noticed that every time you use [[twin fang]] on Cass, you get an auto attack in between the .5 sec cooldowns. So i was wondering how she would fair with a [[lich bane]] as compared to other build options

View (2) Answers

Next AP Mid to learn and why?

Hey, so I can't really decide which champion to learn next after I have finished with Evelynn. I play AP Mid in a fixed 5vs5 team so I need champions who are valuable in organised competitive play. Champions I currently am able to play on a decent...

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