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Karthus Build Guides, Runes and Items

Karthus The Deathsinger

Find the best Karthus build guides for League of Legends S12 Patch 12.15. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Karthus build for the S12 meta. Learn more about Karthus' abilities, skins, or even ask your own questions to the community!

Season 12 Guides // Patch 12.15 & Patch 12.14
9.5
300
Votes
22
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

[70% Winrate] Rank #84 Karthus In The World Guide (MID)

Guide by DingDongGaming updated August 10, 2022
9.4
193
Votes
79
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

[12.14] Karthus Jungle Guide | Monster Jungler

Guide by nZk01 updated July 29, 2022
9.2
144
Votes
8
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

2.4 Million Mastery-Lane Karthus Guide-Season 12

Guide by Hullos updated August 4, 2022
  • In-depth
8.9
137
Votes
23
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

[12.14] Rank 1 Karthus World Guide To Climbing

Guide by ELOSANTA updated August 2, 2022
  • In-depth
7.7
46
Votes
11
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

SEASON 12 Challenger karthus jgl guide

Guide by KamiKZ updated August 2, 2022
New Guide
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

INTING KARTHUS TOP (ALWAYS HAVE IMPACT)

Guide by Sc1 x updated August 7, 2022
  • Off-Meta
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

The Deathsingers Wake - A Karthus Guide

Guide by Aenimatora updated August 1, 2022
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

[12.14] RIFTYXO'S ZYZZILIONARE KARTHUS GUIDE [500 LP EUW]

Guide by riftyxo updated August 8, 2022
Season 12 Builds // Patch 12.15 & Patch 12.14
New Guide
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthussy

Build by Gachis updated August 10, 2022
Season 12 Guides // Other Patches
9.5
112
Votes
14
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Diamond Tank Karthus - Swift Death

Guide by Aqua Dragon updated January 15, 2022
  • In-depth
  • Off-Meta
8.9
621
Votes
26
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

[12.12] Challenger NA & EUW Rank 1 Karthus world | In-depth guide on how play Karthus jungle

Guide by Insightful updated June 28, 2022
  • In-depth
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

[12.10] rank 1 karthus jg guide

Guide by shuralol updated June 2, 2022
7.5
14
Votes
5
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus Jungle adc, support Season 12

Guide by Kyster Draven updated July 10, 2022
6.7
5
Votes
2
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

[12.6] BIGGEST damage Karthus ult MONEY MACHINE

Guide by Lexolus updated April 25, 2022
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Cashout Karthus

Guide by Destruuu updated November 27, 2021
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karfus Gaming WIP

Guide by duowithdeath updated May 5, 2022
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

THIS KARTHUS TRICK WILL GET YOU INFINTE LP

Guide by HirokiiKagome updated February 15, 2022
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

The (near) 1000 Damage per Q Karthus ADC Guide

Guide by Professional Fool updated February 4, 2022
  • Off-Meta
Season 12 Builds // Other Patches
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus Money Printer

Build by Guest updated December 4, 2021
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus

Build by Babledygob updated February 4, 2022
1 2 3 4 5 6 7 8 29 50
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Karthus Build & Runes

If you're looking for the best rune build for Karthus we've got you covered. Below you can find the best items and runes to build for Karthus, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Karthus this is a great resource to quickly get a good rune selection for Patch 12.15. However, if you are a new Karthus player we highly recommend reading through some of the guides above to learn why this build is strong on Karthus!

Patch 12.14: 438954 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 48%

Win Rate 2162 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Treasure Hunter
Treasure Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Second Best

Karthus's 2nd Best Runes 50%

Win Rate 1376 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Third Best

Karthus's 3rd Best Runes 58%

Win Rate 112 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Karthus's Summoner Spells

Karthus's Best Summoner Spells 47%

Win Rate 5964 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 49%

Win Rate 5581 Games

Exhaust Smite

Third Best

Karthus's 3rd Best Summoner Spells 60%

Win Rate 57 Games

Flash Teleport

Karthus's Starters

Karthus's Best Starter Items 48%

Win Rate 5127 Games

  • 1
  • 2
  • 3

Trinket

Karthus's Best Trinket 48%

Win Rate 8294 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 47%

Win Rate 2735 Games

Stealth Ward

Third Best

Karthus's 3rd Best Trinket 50%

Win Rate 1022 Games

Farsight Alteration
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 64%

Win Rate 2240 Games

  • 1
  • 2
Patch 11.20: 494917 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 55%

Win Rate 418 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Second Best

Karthus's 2nd Best Runes 57%

Win Rate 134 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Third Best

Karthus's 3rd Best Runes 54%

Win Rate 330 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Karthus's Summoner Spells

Karthus's Best Summoner Spells 53%

Win Rate 1592 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 53%

Win Rate 168 Games

Flash Teleport

Third Best

Karthus's 3rd Best Summoner Spells 52%

Win Rate 109 Games

Flash Heal

Karthus's Starters

Karthus's Best Starter Items 71%

Win Rate 28 Games

  • 1
  • 2
! Small Sample Size Warning * There is either not a lot of games played on this champion or the builds vary greatly, we have provided the top build but it does not have a high confidence rating so use your own discretion.

Trinket

Karthus's Best Trinket 55%

Win Rate 1137 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 51%

Win Rate 697 Games

Stealth Ward

Third Best

Karthus's 3rd Best Trinket 54%

Win Rate 137 Games

Oracle Lens
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 100%

Win Rate 1 Games

  • 1
! Small Sample Size Warning * There is either not a lot of games played on this champion or the builds vary greatly, we have provided the top build but it does not have a high confidence rating so use your own discretion.
Patch 12.14: 438954 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 61%

Win Rate 195 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Second Best

Karthus's 2nd Best Runes 59%

Win Rate 148 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Third Best

Karthus's 3rd Best Runes 57%

Win Rate 189 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Karthus's Summoner Spells

Karthus's Best Summoner Spells 52%

Win Rate 1547 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 53%

Win Rate 825 Games

Flash Teleport

Third Best

Karthus's 3rd Best Summoner Spells 49%

Win Rate 283 Games

Flash Ignite

Karthus's Starters

Karthus's Best Starter Items 52%

Win Rate 2025 Games

  • 1
  • 2

Trinket

Karthus's Best Trinket 50%

Win Rate 1566 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 54%

Win Rate 1215 Games

Farsight Alteration

Third Best

Karthus's 3rd Best Trinket 57%

Win Rate 201 Games

Oracle Lens
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 65%

Win Rate 268 Games

  • 1
  • 2
Patch 12.14: 438954 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 49%

Win Rate 68 Games

  • 1
  • 2
Inspiration
LoL Path: Inspiration
LoL Rune: First Strike
First Strike
LoL Rune: Magical Footwear
Magical Footwear
LoL Rune: Future's Market
Future's Market
LoL Rune: Cosmic Insight
Cosmic Insight

Domination
LoL Path: Domination
LoL Rune: Ultimate Hunter
Ultimate Hunter
LoL Rune: Eyeball Collection
Eyeball Collection

Second Best

Karthus's 2nd Best Runes 43%

Win Rate 53 Games

Inspiration
LoL Path: Inspiration
LoL Rune: First Strike
First Strike
LoL Rune: Magical Footwear
Magical Footwear
LoL Rune: Minion Dematerializer
Minion Dematerializer
LoL Rune: Cosmic Insight
Cosmic Insight

Domination
LoL Path: Domination
LoL Rune: Ultimate Hunter
Ultimate Hunter
LoL Rune: Eyeball Collection
Eyeball Collection

Third Best

Karthus's 3rd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Karthus's Summoner Spells

Karthus's Best Summoner Spells 54%

Win Rate 242 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 48%

Win Rate 558 Games

Flash Teleport

Third Best

Karthus's 3rd Best Summoner Spells 45%

Win Rate 62 Games

Exhaust Teleport

Karthus's Starters

Karthus's Best Starter Items 48%

Win Rate 613 Games

  • 1
  • 2

Trinket

Karthus's Best Trinket 57%

Win Rate 90 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 48%

Win Rate 588 Games

Stealth Ward

Third Best

Karthus's 3rd Best Trinket 48%

Win Rate 333 Games

Farsight Alteration
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 61%

Win Rate 84 Games

  • 1
  • 2

Karthus Counters

Learn 's counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Karthus guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Karthus Jungle in Plat+ games. The percent shown is the enemy champion's counter rating against Karthus. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.

Karthus Skins

Karthus' Abilities

Questions About Karthus

League of Legends Champions:

Teamfight Tactics Guide