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Karthus Build Guide by Guest

ADC Not for ranked

ADC Not for ranked

Updated on March 9, 2026
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League of Legends Build Guide Author Build Guide By Guest 442 Views 0 Comments
442 Views 0 Comments League of Legends Build Guide Author Karthus Build Guide By Guest Updated on March 9, 2026
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Runes: Autos

1 2
Precision
Lethal Tempo
Triumph
Legend: Alacrity
Last Stand

Inspiration
Biscuit Delivery
Magical Footwear
Bonus:

+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+10-180 Bonus Health

Spells:

1 2
LoL Summoner Spell: Exhaust

Exhaust

LoL Summoner Spell: Flash

Flash

Ability Order Spells waveclear

Threats & Synergies

Threats Synergies
Extreme Major Even Minor Tiny
Show All
None Low Ok Strong Ideal
Extreme Threats
Ideal Synergies
Synergies
Ideal Strong Ok Low None

Champion Build Guide

Not for ranked

By Guest
Matchups you like and avoid
Stronger ADC targets: Zeri, Hwei, Kalista, Nilah, Miss Fortune are among your highest win‑rate matchups bot, since they have limited range or predictable movement for Q.


Avoid blind‑picking into Lux, Seraphine, Sivir, Swain, or Katarina bot, which statistically give Karthus some of his lowest win rates due to heavy poke or mobility.

In fights, stand on the edge of combat with E on and constantly Q the closest safe target; don’t tunnel on hitting carries if it forces bad positioning.



Once you’re low or about to die, move aggressively into the enemy team so that passive + E + Q and a well‑timed R deal maximum damage to everyone.
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