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Spells:
Ignite
Flash
Ability Order
Serpentine Grace (PASSIVE)
Cassiopeia Passive Ability
Announcement
I hope you all enjoy the guides that I provide and I hope they are helpful.
***Updated as of 11/19/11***
Summary
So I was deciding what to do with all my IP that I'd been building up and I took interest in the "New Champion" that was going to be released soon. Her abilities appealed to me, she seemed like a DoT mage that had a spamable attack similar to Urgot's Acid Hunter (I have not played as Urgot but I imagine that ability is pretty fun to use). At first, from just the description, the ultimate seemed to be just another one of those win-game AoE stun ults. However it ended up much different. I purchased her after much thought about buying her, I had heard from the forums that she was underwhelming, but I was up for a challenging champion.
Quick Notes: (These will be assimilated into the rest of the build over time, but for now they will remain somewhat disorganized. Just a few explanations and tips I have for my build.)
After a few practice games trying out items for her, I decided to take an item path somewhat similar to the recommended build, but with some changes.
I personally like getting Doran's Items to start, so I grab

My first ability is Q,


















If you feel like you're dieing too much, or you'd prefer to have more HP, you can build a

Remember, Cassiopeia is a squishy champion, you cannot try to only rely on health or summoner spells to make up for poor positioning decisions. Keep out of harms way, use your abilities from a distance, and avoid any CC. If you're getting hit hard and you feel like you're about to die, use your Zhonya's Hourglass active, it could buy you enough time for your team to help you out, or for you to avoid an ultimate such as Fiddlestick's Crow Storm or MF's Bullet Time. Being a DoT champion, you won't be able to blast any one down to 0 from full HP instantly, but your DoTs are not to be underestimated. I've been able to snatch First Blood on many of my games as Cass, your Q and auto attack can be vicious harassment, and mixed with E can bring a squishy to very low health. I usually


Basically, with your abilities, E>Q>W, and of course get R whenever you can. W, however, is not to be considered a useless spell. I level it up pretty evenly with the others, but the other abilities do take priority over it. For runes I just used the ones from my Malzahar rune page, they seem to work well for him, and he's also somewhat of a DoT mage. Masteries are standard 9/0/21 for casters. For summoner spells, I get ingite to add to your DoTs, and Flash for getting around quick. You can also flash to position yourself for your Ult.
Some basic tactics for effective uses of Cassiopeia's abilities include the following. For farming, Q and W work very well, drop W in a group of stationary minions, I usually use it on the caster minions in the back row, and spam Q at them once or twice, along with the melee minions. For harassing, hit an enemy champion with Q or W, then follow up with E until they are no longer poisoned, in which case, you repeat the process. Personally, I find her ult to be one of the most difficult to use in the game. Where most AoE stuns are used once you're in range, with Cassiopeia, you have to make sure your target is facing you. The range on it is decently small to begin with, so you most likely wont be able to stun an entire team, unlike Amumu or Galio's ult. One thing I once did, if you flash infront of a retreating enemy and turn around at them and ult very very quickly, you can get them with it, but this is still a very tricky ultimate that I am still learning how to use.
Here are a few games played by Vantia, showing how well the build works!


Pros:
Can synergize with other champions that have poison abilities
Passive allows for much ability spamming without much mana cost
Has decent escape mechanisms
She's a snake

Cons:
Ult is very hard to time correctly
Harassing requires you to be dangerously close to enemies
Q can be hard to master, especially against faster moving enemies
Her damage seems to fall later in the game
No real form of burst damage, all abilities are DoT that you must persistently use against your target, which can lead to over extension and death.
(Innate): After casting a spell, any subsequent spellcasts will cost 10% less for 5 seconds. This ability stacks up to 5 times.
This passive will allow you to spam your abilities (within reason) and not have to worry much about your mana. Early game it's not quite as useful because you have fewer abilities to keep the passive in effect. There's not a whole lot to say about her passive, it helps out in the background.

Q: Noxious Blast
Cassiopeia blasts an area with a delayed high damaging poison, dealing magic damage over 3 seconds and granting her movement speed for 2 seconds if she hits a champion.
Cooldown: 3 seconds
Cost: 35 / 45 / 55 / 65 / 75 Mana
Magic Damage: 75 / 115 / 155 / 195 / 235 (+0.9 per Ability Power)
Movement Speed: 15 / 17.5 / 20 / 22.5 / 25 %
Noxious Blast is an excellent harassment tool. While the damage is not instant, it can inflict good damage to your enemy. It is somewhat hard to master this ability, one tip is to place it behind your enemy. When the enemy sees that you've used an ability, their immediate reaction is to retreat backwards, right into your






As mentioned in the champion spot light (one of the few things mentioned), you can use


W: Miasma
Cassiopeia releases a growing cloud of poison that lasts for 7 seconds. Any enemy that passes through it is poisoned for 2 seconds, dealing magic damage each second and slowing them. Continual exposure renews this poison.
Cooldown: 9 seconds
Cost: 70 / 80 / 90 / 100 / 110 Mana
Magic Damage: 25 / 35 / 45 / 55 / 65 (+0.15 per Ability Power)
Slow: 15 / 20 / 25 / 30 / 35 %
Miasma is a good utility spell. While it does have potential for damage, and it's good for farming stationary creeps (I generally use it against caster minions because they stand still most the time), I primarily utilize the slow and poisoning effect of this ability. The slow can be used to save team mates or chase down enemies. You can also slow an entire creep wave, if you put it through their pathway, they will all be poisoned and slowed. You can also use this ability to poison enemies so you can spam





E: Twin Fang
Cassiopeia deals magic damage to her target. If the target is poisoned then Twin Fang's cooldown is reduced to .5 seconds.
Cooldown: 5 seconds
Cost: 50 / 60 / 70 / 80 / 90 Mana
Magic Damage: 60 / 95 / 130 / 165 / 200 (+0.45 per Ability Power)
Twin Fang is one of my favorite abilities that Cassiopeia has. It is spammable with an insanely low CD, provided that your target is poisoned. Basic harassment consists of









R: Petrifying Gaze
Cassiopeia deals magic damage to all enemies in front of her. Enemies facing her are stunned for 2 seconds while enemies facing away are slowed.
Cooldown: 120 seconds
Cost: 120 / 160 / 200 Mana
Magic Damage: 150 / 275 / 400 (+0.6 per Ability Power)
Slow: 40 / 50 / 60 %
Stun: 2 Seconds
This is one of the harder Ultimates to use in the game. One reason is that it requires you, a squishy caster, to get dangerously close to an enemy. If you wish to stun more than one person, you put yourself into even more danger. Another reason is that the enemy must be unaware that you are about to use your ult. Most competent players know how the ult works, and due to the delay on the ult, they can easily turn around, get slowed, then turn back and kill you. The damage on this ability is sub-par to other ults that focus on damage. So you maybe be thinking, 'gee Furber, how do I use this ult well?'. Well the way I see it, unless the enemy team is ******ed, you cant just run up to the enemy team and freeze them all. This ult is good for turning a push around. When your team is retreating from their team, look for an opportunity to turn back quickly and ult their team. If done correctly, the result will be similar to an Amumu ult. Your team can turn around and beat on the enemies for 2 full seconds. This should be enough to gain the advantage in the team fight, and hopefully you will win. Reptiile also point out that, on a smaller scale, you can help save a friend that is running away from an enemy. Turn quickly and stop the pursuer. Then you and your ally can either continue running away, or turn and fight the enemy.
As far as a 1v1 ult goes, if you're able to hit your enemy with it, then you will do well, but being on a 2 minute CD, it is not always optimal to use this in a 1v1 situation in the open field. I've found it to be amazing against face checkers. Stay in the bush until they get right up to it, then Ult them in the face, and proceed to spam your abilities on them until death. In terms of ganking, you will need to use

These summoner spells are in order of most recommended to least recommended













Masteries

I go into Offense 9 points to get the Magic Penetration, as well as some to get some CDR.
The rest of the points go to Utility for things like Mana, Mana regen, CDR, a little movement speed, improve Flash (you can get the Ghost mastery if you use Ghost instead). I chose to get the improve Neutral monster buffs for the Blue Buff. I always go for the blue buff whenever I get the chance, it makes Cassiopeia's spam alot more efficient and frequent during team fights. With the 25% CDR and increased mana regen, you can spam out your abilities even more than before.
Rune Choice
For Marks, I get magic pen. All of Cassiopeia's abilities are damaging spells, so the more magic pen you have, the better.
For Glyphs, I get straight CDR, this allows for more frequent spam of abilities, as well as a slightly lower CD on your Ult. AP runes can be used as an alternative to this.
For Seals, I get mana regen per level. This helps him keep up his mana, Cassiopeia's spam can eventually run you dry of mana.
For Quintessences, I choose magic penetration. This makes your abilities penetrate even more of the enemies magic resistance. Other options for quints include: Straight HP, Straight AP, CDR, or whatever you prefer to be your caster runes.
Item Choice
My first item is a

Early game your build should look like this:

Next, you want to get Catalyst of the Protector. This helps with your squishy-ness and aids in your lane sustainability. You will eventually turn this into a Banshee's Veil, or you could make it into a Rod of Ages
Third, I pick up

At this point, your build should be:


Your 4th item is




After that, you can finish your boots into

You should be hitting pretty well with this build:



The next item is

Next, you go for

Now I would like to insert that you should have sold your

You'll be hitting hard with a build like this:




My next item is a

Last item is really your choice, I prefer to get a Lich Bane. My reasoning for this item is that A) It gives you movement speed so you can be quicker about moving around while in combat. B) It gives you +80 AP which helps your ability strength. C)The passive that affects your auto attack. When using your




Other options include items for more Mpen like Abyssal Scepter or Void Staff
Your final build should look like this:








Other Items
There are a few other items that other Cassiopiea players consider getting. I will give my opinion on these items.

Rod of Ages
Good HP, Mana, and AP. Imo, It's more of a bulky caster and AP tank item, for characters like Kassadin and Cho'gath. I prefer to upgrade my catalyst the protectorCatalyst into a


Will of The Ancients
This item gives AP + Spell Vamp in addition to an aura that can help allies. I've seen more people consider this item, I suppose it could work out pretty well. The AP ofc is helpful, and the spell vamp can increase your sustain, as well as potentially help you in a fight. Good item, I just prefer other items instead.

Lich Bane
Gives you some AP, MR, Movement Speed, Active that enhances your autoattack. If you utilize the passive of this item, it can potentially be very strong. Using an auto attack in between a Q and/or E can be pretty powerful if you have this item. However, this is pretty hard to pull off, it would require a lot of effort. If you're really dedicated and you utilize the passive, this item may be worth it, but other wise I wouldn't bother buying it.

Moonflair Spellblade
This is a great item to get if the enemy team has a lot of CC. If you don't want to substitute



Morello's Evil Tome
Great item if you're looking to build lots of CDR. Combined with


Haunting Guise
This item is good for HP AP and spell pen. It's a pretty small inexpensive item, so if you just need that little extra boost, you can get this item. However, late game if you have all 6 items, you should sell this item and get something better like a

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