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I do think cash back, biscuit delivery, and jack of all trades are viable rune slot options for the inspiration tree. They're all worth at least looking into.
Cash back accelerates the great 3 item spikes like the unending, fibul, spirit or the roa, navori, hullbreaker.
Biscuit delivery provides 3 free potions in lane and provides permanent max hp with a total gold value of 240g, not including the active healing. The active healing also stacks with health potions to provide a surprising amount of healing that can be used in combat to heal up. It can often let you get one more W proc which completely changes the fight, and it really lets you juice last stand because the biscuits heal based on % missing hp.
Jack of all trades is typically standard in the roa, navori build, as you are cranking out unique stats and can easily reach max stacks while building your third item. (While it's easier to reach max stacks building a defensive item like spirit visage over hullbreaker, it is still possible to reach before finishing the item)
I'm glad u found the guide useful!
I really needed this.