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Is it no longer possible or can I at least still play it in my low Elo (Bronze/Silver)?
And if so, what is the build and the runes?
Of course, but i would 100% say that normal ad / bruiser senna is the way currently.
If you wanna play enchanter, these are the runes:
Aery - Arcanist - Absolute Focus - Gathering Storm/Scorch (depending if you want late or early power)
Secondary runes are resolve with:
Font of Life - Revitalize
or
Bone Platting - Revitalize (Bone Platting gives you better early game against hook champs like Naut/Pyke)
As for item build:
Moonstone - Helia - Locket - Support-Items depending on your team (Ardent/Staff of Flowing Water)
It's changed now, thanks for telling me <3