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If you want to take extended fights, you run Conqueror 100% of the time. Lethal Tempo is a completely fake value rune on this champion for several massive reasons:
Rengar is not Tryndamere or Jax: You do not win fights by standing still and right-clicking a brick wall 15 times in a row. Rengar is an ability-based skirmisher. He wins by weaving spells, kiting in and out of bushes, and resetting auto-attack animations with Q. Conqueror boost entire kit with raw AD and healing.
Every time you press W to heal or E to slow, you lock yourself out of auto-attacking for a split second. You literally cannot utilize the high attack speed from Lethal Tempo because your own casting animations interrupt it.
The Bonus Range: Your entire laning phase revolves around jumping out of a bush. Why do you need a rune to give you 50 extra melee attack range when you're already flying across the screen? Lethal Tempo forces you to stay glued to the target, which completely ruins your bush-kiting micro.
Level 1 Cheese Argument is not really a thing: The only scenario where Lethal Tempo wins a level 1 fight is if the enemy player turns their brain completely off, walks into the middle of the lane, and brainlessly auto-battles you. Anyone with a functioning keyboard is just going to space you out with Q, slow you, and farm from a screen away. If they respect your level 1, you are stuck playing the next 25 minutes of the game without a real keystone. Rengar's passive already gives him a massive built-in attack speed steroid on his Empowered Q anyway—you need raw AD from Conqueror to make those fast hits actually hurt.
Conqueror: Take this for raw AD scaling on your whole ability kit and the essential 8% healing to survive long fights of against bruisers/tanks.
Fleet Footwork: Take this for hit-and-run chunking, pure lane sustain, and god-tier spacing against ranged/poke matchups.
PTA and Hail of Blades: Gives you burst damage but zero sustain. If the tank builds one armor component, your burst is gone and you get run down.
About fleet: I agree 100%
Anyways thanks for taking the time to read through and I value your input ofc - this is my first guide ever so I am really grateful for feedback and look forward to improve it over time. Right now its just a first version.
I also want to create a excel spreadsheet for all the matchups and will link it here aswell.
Thanks for your input and time - much appreciated.