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p.s. sorry it took so long for this edit, I've been really busy in RL :P
and as always.. Happy Smiting fellow Karthus freaks! :D
as a player who has mained with karthus for about 6-7 months now i feel my input is needed. as great as this build is, its just not as good as playing karthus in mid or solo lane. there are plenty of people better suited for the jungle. sure karthus has amazing ganking abilities with his wall+ lay waste, but if your good enough with karthus you should have no problem killing your opponent in mid and walking over for a gank in top or bot. as for the unsuspected ult, people will see that you have chosen karthus and will be waiting for the global ult at all times. so his ult is never really a surprise when you use it.
i tried this build out before i commented so i wouldnt seem like a troll, and the results were terrible. you get ganked due to the fact your a squishy little karthus with no escape until lvl 7 if you follow this build to the letter. you get no early game kills which results in less gold, rather than having consistent minion waves coming.
all and all im sorry to say i disapprove of this build, it just isnt nearly as effective as laning, which is where you belong.