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With the runes, building ALL AP means you are sacrificing on several other advantages you could have, as well as efficiency. Magic Pen Marks are a must, though AS runes would work very well also; Clarity seals are important on cho, though I can see dodge or armor seals working well as well; CDR glyphs are amazing with chogath... If you get flat CDR glyphs, this build would give Chogath a whopping 33% CDR.
Defensive Masteries would greatly benefit this type of cho. When I go AS chogath, I usually go 9-21-0, so the defense offsets the builds inherent squishy-ness.
With summoner skills, there are several choices involved here, however I feel Exhaust is a must. With AS cho, you'll be going head to head with other natural auto-attackers, and this really gives you an edge. Also, if you begin an assault with exhaust, it makes Rupture ridiculously easy to hit with.
Finally, I'd like to suggest replacing Rod of Ages with a defensive item for the final item. Rylai's fulfills the same needs as RoA does at that point, and I've had greater success with it because it gives more hp. For a defensive item, Guardian Angel is amazing, but there are other strong choices such as Banshee's Veil as well.
Ignite, Ghost and Teleport! XD
In twisted treeline I ownd a ranked with Wit's End, malady, guardian angel and a rylai's.
Pure ownage!