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I think this build is great, but there ain't no alternative items or anything. You should tell more about items, summoner spells etc.......
And make it more CLEAN it's hard to read if you are a newbie (no offence). But still I give +1. This is for that this is a new guide, so it doen't need to be perfect, but you need to make it better all the time.
The reason there are no alternative items is because these are the items Karma really needs. I left the last two slots open, because those are up to you, depending on your enemy team. Also, I don't have alternative items because Karma is only a useful support as long as she has tons and tons of AP. Otherwise she is really useless.
And make it more CLEAN it's hard to read if you are a newbie (no offence). But still I give +1. This is for that this is a new guide, so it doen't need to be perfect, but you need to make it better all the time.