From personal experience of pairing up with the TF who wrote this guide, pay attention! I've seen him go 39/1/(can't remember assists, but you can guess). I've gotten used to not judging my game by my kill count, but by my assist count...

Vampirism helps with this build as you will kill a lot of minions, considering the other options for this single mastery point, it seems to me to be the best option. I absolutely do not like Doran's Blade in any build I go for, be it this one, AD or any other AD champion. It blows a lot of gold in the wind for the small bonus that could be easily subverted by being a little more careful, I've never used this item again after my few weeks of LoL and I never will. If you think otherwise of if you think you might get a few more minutes on the field or even kills in the first few minutes, that's fine by me. It does not do anything for me though.

Scars_and_flames
you're right, both are typos, I meant to say the bloodrazor gives def and for some reason wrote HP as well, must have mixed it up somewhere. I'll correct the typoes tonight.

OK,well,Seals are really useless,rather pop there some armor or if u like that much attack speed,get there Greater Seel of Alacrity . AS is second thing... U are having with full build 2.5 AS or what..? 3rd... Doran's Blade is not useless.. Please do not say it again. ;) HP,Dmg and Lifesteal bonus is usefull for many AD heroes but (yeah,agreed this time) not for AS TF... Maybe for hybrid,but Doran's Ring would be better choice. YOu got Vampirism there and i wish to ask you. Why? You wrote DB is useless so u don't like lifesteal and rest of this. so why y u took This masterie? Why not bonus DMG? (1.5% is best for as but still) Rather Dmg then lifesteal in this.

check your items again. first, it's dorans, not dorians. second, madreds bloodrazor doesnt give any hp

(havent looked for any other mistakes though)

Your seals are useless, and runes are more for early game more than late game. It will seem like your not getting much but when you start with almost nothing good runes can make your early game.