This may seem odd, but i'm going to say Maokai. Support Maokai is what i usually play, and ive had great success playing with talented Vayne's. The logic behind it is that maokai gives support through aggro. Sapling toss has a huge range, and eventually enemy champs will not want to come close to the creep wave for fear of being 'sploded by plants. Good zoning by mao leaves vayne free to farm and last hit to her heart's content without fear of being shot at. And when the enemy team gets antsy and attempts to come take their rightful place back in the creep wave, mao can root them in place and cc them to hell while vayne fills them full of arrows. All in all this is a fairly passive way to play vayne, but doing things this way ensures that you outfarm your opponents which leads to kills mid-late game, and also locks the enemy team out of their own farm, which makes them underpowered mid-late game, which again makes Vayne happy.
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Blitzcrank - Vayne.
blitz can't stop vayne from being blown up as well as other supports. he also has no sustain. The only thing he does really well is zone.